[HTML][HTML] Targeting mutant p53 for cancer therapy: direct and indirect strategies
J Hu, J Cao, W Topatana, S Juengpanich, S Li… - Journal of hematology & …, 2021 - Springer
TP53 is a critical tumor-suppressor gene that is mutated in more than half of all human
cancers. Mutations in TP53 not only impair its antitumor activity, but also confer mutant p53 …
cancers. Mutations in TP53 not only impair its antitumor activity, but also confer mutant p53 …
[HTML][HTML] Blood-derived lncRNAs as biomarkers for cancer diagnosis: the Good, the Bad and the Beauty
C Badowski, B He, LX Garmire - NPJ precision oncology, 2022 - nature.com
Cancer ranks as one of the deadliest diseases worldwide. The high mortality rate associated
with cancer is partially due to the lack of reliable early detection methods and/or inaccurate …
with cancer is partially due to the lack of reliable early detection methods and/or inaccurate …
Non-coding RNAs in development and disease: background, mechanisms, and therapeutic approaches
J Beermann, MT Piccoli, J Viereck… - Physiological …, 2016 - journals.physiology.org
Advances in RNA-sequencing techniques have led to the discovery of thousands of non-
coding transcripts with unknown function. There are several types of non-coding linear …
coding transcripts with unknown function. There are several types of non-coding linear …
Roles, functions, and mechanisms of long non-coding RNAs in cancer
Y Fang, MJ Fullwood - Genomics, Proteomics and …, 2016 - academic.oup.com
Long non-coding RNAs (lncRNAs) play important roles in cancer. They are involved in
chromatin remodeling, as well as transcriptional and post-transcriptional regulation, through …
chromatin remodeling, as well as transcriptional and post-transcriptional regulation, through …
[HTML][HTML] The functions and unique features of LncRNAs in cancer development and tumorigenesis
K Taniue, N Akimitsu - International journal of molecular sciences, 2021 - mdpi.com
Over the past decades, research on cancer biology has focused on the involvement of
protein-coding genes in cancer development. Long noncoding RNAs (lncRNAs), which are …
protein-coding genes in cancer development. Long noncoding RNAs (lncRNAs), which are …
Long non-coding RNAs and complex diseases: from experimental results to computational models
LncRNAs have attracted lots of attentions from researchers worldwide in recent decades.
With the rapid advances in both experimental technology and computational prediction …
With the rapid advances in both experimental technology and computational prediction …
DIANA-LncBase v2: indexing microRNA targets on non-coding transcripts
MD Paraskevopoulou, IS Vlachos… - Nucleic acids …, 2016 - academic.oup.com
Abstract microRNAs (miRNAs) are short non-coding RNAs (ncRNAs) that act as post-
transcriptional regulators of coding gene expression. Long non-coding RNAs (lncRNAs) …
transcriptional regulators of coding gene expression. Long non-coding RNAs (lncRNAs) …
Long noncoding RNAs as biomarkers in cancer
L Bolha, M Ravnik-Glavač, D Glavač - Disease markers, 2017 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are a relatively well‐characterized class of noncoding
RNA (ncRNA) molecules, involved in the regulation of various cell processes, including …
RNA (ncRNA) molecules, involved in the regulation of various cell processes, including …
TANRIC: an interactive open platform to explore the function of lncRNAs in cancer
Long noncoding RNAs (lncRNA) have emerged as essential players in cancer biology.
Using recent large-scale RNA-seq datasets, especially those from The Cancer Genome …
Using recent large-scale RNA-seq datasets, especially those from The Cancer Genome …
[HTML][HTML] Long non-coding RNAs (lncRNAs) in spermatogenesis and male infertility
M Joshi, S Rajender - Reproductive Biology and Endocrinology, 2020 - Springer
Abstract Background Long non-coding RNAs (lncRNAs) have a size of more than 200 bp
and are known to regulate a host of crucial cellular processes like proliferation …
and are known to regulate a host of crucial cellular processes like proliferation …