Biological imaging of chemical bonds by stimulated Raman scattering microscopy
All molecules consist of chemical bonds, and much can be learned from mapping the
spatiotemporal dynamics of these bonds. Since its invention a decade ago, stimulated …
spatiotemporal dynamics of these bonds. Since its invention a decade ago, stimulated …
Vibrational spectroscopic imaging of living systems: An emerging platform for biology and medicine
BACKGROUND Biomolecules can serve as natural labels for microscopy by measuring their
molecular vibration spectra in living cells and tissues. However, the transition from …
molecular vibration spectra in living cells and tissues. However, the transition from …
Instant diagnosis of gastroscopic biopsy via deep-learned single-shot femtosecond stimulated Raman histology
Gastroscopic biopsy provides the only effective method for gastric cancer diagnosis, but the
gold standard histopathology is time-consuming and incompatible with gastroscopy …
gold standard histopathology is time-consuming and incompatible with gastroscopy …
Cholesteryl ester accumulation induced by PTEN loss and PI3K/AKT activation underlies human prostate cancer aggressiveness
Altered lipid metabolism is increasingly recognized as a signature of cancer cells. Enabled
by label-free Raman spectromicroscopy, we performed quantitative analysis of lipogenesis …
by label-free Raman spectromicroscopy, we performed quantitative analysis of lipogenesis …
Stimulated Raman scattering: from bulk to nano
Stimulated Raman scattering (SRS) describes a family of techniques first discovered and
developed in the 1960s. Whereas the nascent history of the technique is parallel to that of …
developed in the 1960s. Whereas the nascent history of the technique is parallel to that of …
Microsecond fingerprint stimulated Raman spectroscopic imaging by ultrafast tuning and spatial-spectral learning
Label-free vibrational imaging by stimulated Raman scattering (SRS) provides
unprecedented insight into real-time chemical distributions. Specifically, SRS in the …
unprecedented insight into real-time chemical distributions. Specifically, SRS in the …
Hyperspectral imaging with stimulated Raman scattering by chirped femtosecond lasers
D Fu, G Holtom, C Freudiger, X Zhang… - The Journal of Physical …, 2013 - ACS Publications
Raman microscopy is a quantitative, label-free, and noninvasive optical imaging technique
for studying inhomogeneous systems. However, the feebleness of Raman scattering …
for studying inhomogeneous systems. However, the feebleness of Raman scattering …
Single cell optical imaging and spectroscopy
AS Stender, K Marchuk, C Liu, S Sander… - Chemical …, 2013 - ACS Publications
In his 1665 treatise, Micrographia, Robert Hooke described the many observations he had
made using a microscope, including compartment-like structures in cork samples that he …
made using a microscope, including compartment-like structures in cork samples that he …
Coherent Raman scattering microscopy in biology and medicine
Advancements in coherent Raman scattering (CRS) microscopy have enabled label-free
visualization and analysis of functional, endogenous biomolecules in living systems. When …
visualization and analysis of functional, endogenous biomolecules in living systems. When …
Developments in spontaneous and coherent Raman scattering microscopic imaging for biomedical applications
First, the potential role of Raman-based techniques in biomedicine is introduced. Second,
an overview about the instrumentation for spontaneous and coherent Raman scattering …
an overview about the instrumentation for spontaneous and coherent Raman scattering …