There is currently an unmet need for better biomarkers across the spectrum of renal
diseases. In this paper, we revisit the role of beta-2 microglobulin (β2M) as a biomarker in …

Toxin retention is felt to be a major contributor to the development of uremia in patients with
advanced chronic kidney disease and end-stage renal disease (ESRD). Uremic retention …

Blood pressure (BP) and volume control are critical components of dialysis care and have
substantial impacts on patient symptoms, quality of life, and cardiovascular complications …

In patients with ESRD, residual kidney function (RKF) contributes to achievement of
adequate solute clearance. However, few studies have examined RKF in patients on …

Mineralocorticoid receptor antagonists have beneficial effects on left ventricular remodeling,
cardiac fibrosis, and arrhythmia in heart failure, but efficacy and safety in dialysis patients is …

Rationale & Objective Thrice-weekly hemodialysis (HD) is the most common treatment
modality for kidney failure in the United States. We conducted a pilot study to assess the …

Background: Residual kidney function (RKF) conveys a survival benefit among dialysis
patients, but the mechanism remains unclear. Improved volume control, clearance of protein …

Frailty has been defined as a state of increased vulnerability as a consequence of deficit
accumulation. Frailty screening has not yet been widely implemented into routine …

Chronic kidney disease (CKD) is generally regarded as a final common pathway of several
renal diseases, often leading to end-stage kidney disease (ESKD) and a need for renal …

Novel conservative management of chronic kidney disease via... : Current Opinion in
Nephrology and Hypertension Novel conservative management of chronic kidney disease …