Salience signaling and stimulus scaling of ventral tegmental area glutamate neuron subtypes

DJ McGovern, A Phillips, A Ly, ED Prévost, L Ward… - bioRxiv, 2024 - biorxiv.org
Ventral tegmental area (VTA) glutamatergic neurons participate in reward, aversion, drug-
seeking, and stress. Subsets of VTA VGluT2+ neurons are capable of co-transmitting …

Aging disrupts the coordination between mRNA and protein expression in mouse and human midbrain

SA Buck, SJ Mabry, JR Glausier, T Banks-Tibbs… - bioRxiv, 2024 - biorxiv.org
Age-related dopamine (DA) neuron loss is a primary feature of Parkinsons disease.
However, it remains unclear whether similar biological processes occur during healthy …