Nanoparticle-based drug delivery system: the magic bullet for the treatment of chronic pulmonary diseases

S Pramanik, S Mohanto, R Manne… - Molecular …, 2021 - ACS Publications
Chronic pulmonary diseases encompass different persistent and lethal diseases, including
chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), cystic …

Emerging technologies and commercial products in exosome-based cancer diagnosis and prognosis

M Mohammadi, H Zargartalebi, R Salahandish… - Biosensors and …, 2021 - Elsevier
Academic and industrial groups worldwide have reported technological advances in
exosome-based cancer diagnosis and prognosis. However, the potential translation of these …

Magnetic particle targeting for diagnosis and therapy of lung cancers

M Saadat, MKD Manshadi, M Mohammadi… - Journal of Controlled …, 2020 - Elsevier
Over the past decade, the growing interest in targeted lung cancer therapy has guided
researchers toward the cutting edge of controlled drug delivery, particularly magnetic …

Euler-Lagrange numerical simulation of improved magnetic drug delivery in a three-dimensional CT-based carotid artery bifurcation

H Aryan, B Beigzadeh, M Siavashi - Computer Methods and Programs in …, 2022 - Elsevier
Background and objective Magnetic drug targeting (MDT) is a promising method to improve
the therapy efficiency for cardiovascular diseases (CVDs) and cancers. In MDT, therapeutic …

Design of a multilayer lung chip with multigenerational alveolar ducts to investigate the inhaled particle deposition

Y Qiu, C Lu, F Bao, G Hu - Lab on a Chip, 2023 - pubs.rsc.org
We present the development and application of a multilayer microfluidic lung chip designed
to accurately replicate the human respiratory bronchi, providing an innovative platform for …

Coupling magnetic torque and force for colloidal microbot assembly and manipulation

CJ Zimmermann, AJ Petruska… - Advanced Intelligent …, 2023 - Wiley Online Library
For targeted transport in the body, biomedical microbots (μbots) must move effectively in
three‐dimensional (3D) microenvironments. Swimming μbots translate via asymmetric or …

Effect of tissue permeability and drug diffusion anisotropy on convection-enhanced delivery

W Zhan, F Rodriguez y Baena, D Dini - Drug delivery, 2019 - Taylor & Francis
Although convection-enhanced delivery (CED) can successfully facilitate a bypass of the
blood brain barrier, its treatment efficacy remains highly limited in clinic. This can be partially …

An experimental study of respiratory aerosol transport in phantom lung bronchioles

AK Mallik, S Mukherjee, MV Panchagnula - Physics of Fluids, 2020 - pubs.aip.org
The transport and deposition of micrometer-sized particles in the lung is the primary
mechanism for the spread of aerosol borne diseases such as corona virus disease-19 …

Numerical studies on magnetic driven targeted drug delivery in human vasculature

NK Tamboli, JS Murallidharan - Journal of the Indian Institute of Science, 2024 - Springer
Magnetic driven targeted drug delivery (TDD) involves the manipulation of magnetic drug
carriers, such as nano/micro particles or bubbles, within the body using external magnetic …

Recent Developments in Aerosol Pulmonary Drug Delivery: New Technologies, New Cargos, and New Targets

IR Woodward, CA Fromen - Annual Review of Biomedical …, 2024 - annualreviews.org
There is nothing like a global pandemic to motivate the need for improved respiratory
treatments and mucosal vaccines. Stimulated by the COVID-19 pandemic, pulmonary …