Reactive oxygen species (ROS) are a heterogeneous group of molecules that are generated
by mature myeloid cells during innate immune responses, and are also implicated in normal …

Myeloid leukemic cells are intrinsically under oxidative stress due to impaired reactive
oxygen species (ROS) homeostasis, a common signature of several hematological …

The development of strategies to eradicate primary human acute myelogenous leukemia
(AML) cells is a major challenge to the leukemia research field. In particular, primitive …

OBJECTIVES: To evaluate the oxidative status and antioxidant defense in patients with
acute lymphoblastic leukemia (ALL). DESIGN AND METHODS: We measured …

Reactive oxygen species (ROS) play both positive and negative roles in the proliferation and
survival of a cell. This dual nature has been exploited by leukemia cells to promote growth …

Among the different mechanisms involved in oxidative stress, protein carbonylation and lipid
peroxidation are both important modifications associated with the pathogenesis of several …

SOD-like activity of CeO 2 nanoparticles (Ce NPs) is driven by Ce 3+/Ce 4+, high oxidative
stress can oxidize Ce 3+ to reduce the ratio of Ce 3+/Ce 4+, inactivating the SOD activity of …

It has become apparent that regulation of ROS is important in cell signaling and
homeostasis. Accumulation of ROS triggers oxidative stress in various cell types and …

Abstract Superoxide anion (O 2•-), hydrogen peroxide (H 2 O 2), hydroxyl radical (• OH) are
the main components of endogenous reactive oxygen species (ROS), while• OH shows the …

Reactive oxygen species (ROS) can be generated by defective endogenous reduction of
oxygen by cellular enzymes or in the mitochondrial respiratory pathway, as well as by …