Adult neurogenesis is a multistage process by which neurons are generated and integrated
into existing neuronal circuits. In the adult brain, neurogenesis is mainly localized in two …

Multiciliated cells (MCC) project dozens to hundreds of motile cilia from the cell surface to
generate fluid flow across epithelial surfaces or turbulence to promote the transport of …

Simple Summary In normal cells, p53 is a protein which regulates the cell cycle progression
to ensure normal cell division, growth, and development. However, in cancer, changes in the …

Mature multiciliated ependymal cells line the cerebral ventricles where they form a partial
barrier between the cerebrospinal fluid (CSF) and brain parenchyma and regulate local CSF …

Idiopathic scoliosis (IS) is the most common spinal deformity diagnosed in childhood or early
adolescence, while the underlying pathogenesis of this serious condition remains largely …

Multiciliated cells (MCCs) are specialized in fluid propulsion through directional beating of
myriads of superficial motile cilia, which rest on modified centrioles named basal bodies …

Cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy (CADASIL) is a rare hereditary cerebrovascular disease caused by a …

Abstract p73 and p63 are members of the p53 family that exhibit overlapping and distinct
functions in development and homeostasis. The evaluation of p73 and p63 isoform …

Recent studies have shown that there exists a direct relationship between environmental
pollutants (PM2. 5, smog), the respiratory system, and the morbidity and mortality of …

ABSTRACT p73 (TP73) belongs to the p53 family of transcription factors. Its gene locus
encodes two opposing types of isoforms, the transcriptionally active TAp73 class and the …