FAPI PET: fibroblast activation protein inhibitor use in oncologic and nononcologic disease
Y Mori, K Dendl, J Cardinale, C Kratochwil, FL Giesel… - Radiology, 2023 - pubs.rsna.org
Gallium 68 (68Ga)–labeled fibroblast activation protein (FAP) inhibitor (FAPI) PET is based
on the molecular targeting of the FAP, which is known to be highly expressed in the major …
on the molecular targeting of the FAP, which is known to be highly expressed in the major …
[HTML][HTML] Fibroblast activation protein-based theranostics in cancer research: a state-of-the-art review
In recent years, quinoline-based fibroblast activation protein (FAP) inhibitors (FAPI) have
shown promising results in the diagnosis of cancer and several other diseases, making them …
shown promising results in the diagnosis of cancer and several other diseases, making them …
Preclinical evaluation of FAP-2286 for fibroblast activation protein targeted radionuclide imaging and therapy
D Zboralski, A Hoehne, A Bredenbeck… - European journal of …, 2022 - Springer
Purpose Fibroblast activation protein (FAP) is a membrane-bound protease that has limited
expression in normal adult tissues but is highly expressed in the tumor microenvironment of …
expression in normal adult tissues but is highly expressed in the tumor microenvironment of …
Clinical summary of fibroblast activation protein inhibitor-based radiopharmaceuticals: cancer and beyond
Fibroblast activation protein (FAP) is a type II membrane-bound glycoprotein which is
overexpressed in cancer-associated fibroblasts and activated fibroblasts at wound …
overexpressed in cancer-associated fibroblasts and activated fibroblasts at wound …
[18F]FAPI-42 PET imaging in cancer patients: optimal acquisition time, biodistribution, and comparison with [68Ga]Ga-FAPI-04
K Hu, L Wang, H Wu, S Huang, Y Tian, Q Wang… - European Journal of …, 2022 - Springer
Abstract Purpose [18 F] FAPI-42 is a new fibroblast activation protein (FAP)-specific tracer
used for cancer imaging. Here, we describe the optimal acquisition time and in vivo …
used for cancer imaging. Here, we describe the optimal acquisition time and in vivo …
Morphological, dynamic and functional characteristics of liver pseudolesions and benign lesions
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths
worldwide and one of the most common causes of death among patients with cirrhosis …
worldwide and one of the most common causes of death among patients with cirrhosis …
Current research topics in FAPI theranostics: a bibliometric analysis
AF van den Hoven, RGM Keijsers, MGEH Lam… - European Journal of …, 2023 - Springer
Purpose The study aimed to provide a comprehensive bibliometric overview of the current
scientific publications on fibroblast activation protein inhibitor (FAPI) positron emission …
scientific publications on fibroblast activation protein inhibitor (FAPI) positron emission …
Head-to-Head Comparison of Fibroblast Activation Protein Inhibitors (FAPI) Radiotracers versus [18F]F-FDG in Oncology: A Systematic Review
G Treglia, B Muoio, H Roustaei, Z Kiamanesh… - International Journal of …, 2021 - mdpi.com
Several recent studies comparing radiolabeled fibroblast activation protein inhibitors (FAPI)
and fluorine-18 fluorodeoxyglucose ([18F] F-FDG) as positron emission tomography (PET) …
and fluorine-18 fluorodeoxyglucose ([18F] F-FDG) as positron emission tomography (PET) …
Radioligands targeting fibroblast activation protein (FAP)
T Lindner, FL Giesel, C Kratochwil, SE Serfling - Cancers, 2021 - mdpi.com
Simple Summary FAP-targeted radiotracers, recently introduced in cancer treatment,
accumulate in Cancer-Associated Fibroblasts (CAFs). CAFs are present in tumor lesions but …
accumulate in Cancer-Associated Fibroblasts (CAFs). CAFs are present in tumor lesions but …
18F- or 177Lu-labeled bivalent ligand of fibroblast activation protein with high tumor uptake and retention
H Li, S Ye, L Li, J Zhong, Q Yan, Y Zhong… - European Journal of …, 2022 - Springer
Purpose Fibroblast activation protein (FAP) has become a promising cancer-related target
for diagnosis and therapy. The aim of this study was to develop a bivalent FAP ligand for …
for diagnosis and therapy. The aim of this study was to develop a bivalent FAP ligand for …