Global burden and epidemiology of Barrett oesophagus and oesophageal cancer

AP Thrift - Nature reviews Gastroenterology & hepatology, 2021 - nature.com
Oesophageal cancer is a global health problem; in 2018 there were more than 572,000
people newly diagnosed with oesophageal cancer worldwide. There are two main …

Epidemiology of esophageal squamous cell carcinoma

CC Abnet, M Arnold, WQ Wei - Gastroenterology, 2018 - Elsevier
Esophageal squamous cell carcinoma (ESCC) accounts for about 90% of the 456,000
incident esophageal cancers each year. Regions of high incidence include Eastern to …

Air pollution, genetic factors, and the risk of lung cancer: a prospective study in the UK Biobank

Y Huang, M Zhu, M Ji, J Fan, J Xie, X Wei… - American journal of …, 2021 - atsjournals.org
Rationale: Both genetic and environmental factors contribute to lung cancer, but the degree
to which air pollution modifies the impact of genetic susceptibility on lung cancer remains …

Esophageal carcinoma

AK Rustgi, HB El-Serag - New England Journal of Medicine, 2014 - Mass Medical Soc
The 5-year survival rate in esophageal cancer, although poor, has improved over the past
decade. This review discusses the epidemiologic aspects, pathogenesis, prevention, and …

Genetic landscape of esophageal squamous cell carcinoma

YB Gao, ZL Chen, JG Li, XD Hu, XJ Shi, ZM Sun… - Nature …, 2014 - nature.com
Esophageal squamous cell carcinoma (ESCC) is one of the deadliest cancers. We
performed exome sequencing on 113 tumor-normal pairs, yielding a mean of 82 non-silent …

[HTML][HTML] Epidemiology of esophageal cancer

Y Zhang - World journal of gastroenterology: WJG, 2013 - ncbi.nlm.nih.gov
Esophageal cancer (EsC) is one of the least studied and deadliest cancers worldwide
because of its extremely aggressive nature and poor survival rate. It ranks sixth among all …

Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors

BS Melin, JS Barnholtz-Sloan, MR Wrensch… - Nature …, 2017 - nature.com
Genome-wide association studies (GWAS) have transformed our understanding of glioma
susceptibility, but individual studies have had limited power to identify risk loci. We …

Global trends in esophageal cancer

GK Malhotra, U Yanala, A Ravipati… - Journal of surgical …, 2017 - Wiley Online Library
BACKGROUND AND OBJECTIVES Esophageal Cancer (EC) is a lethal malignancy with
poor prognosis and significant variations in the incidence, mortality, and histopathology …

Systems genetics approaches to understand complex traits

M Civelek, AJ Lusis - Nature Reviews Genetics, 2014 - nature.com
Abstract Systems genetics is an approach to understand the flow of biological information
that underlies complex traits. It uses a range of experimental and statistical methods to …

[HTML][HTML] Silencing of long noncoding RNA MALAT1 by miR-101 and miR-217 inhibits proliferation, migration, and invasion of esophageal squamous cell carcinoma …

X Wang, M Li, Z Wang, S Han, X Tang, Y Ge… - Journal of biological …, 2015 - ASBMB
MALAT1, a highly conserved long noncoding RNA, is deregulated in several types of
cancers. However, its role in esophageal squamous cell carcinoma (ESCC) and its …