Tablet scoring: current practice, fundamentals, and knowledge gaps

ER Jacques, P Alexandridis - Applied Sciences, 2019 - mdpi.com
Oral solid dosage formulations and/or tablets have remained the preferred route of
administration by both patients and health care practitioners. Oral tablets are easy to …

Practical problems with medication use that older people experience: a qualitative study

K Notenboom, E Beers… - Journal of the …, 2014 - Wiley Online Library
Objectives To identify the practical problems that older people experience with the daily use
of their medicines and their management strategies to address these problems and to …

[HTML][HTML] The accuracy, precision and sustainability of different techniques for tablet subdivision: breaking by hand and the use of tablet splitters or a kitchen knife

DA van Riet-Nales, ME Doeve, AE Nicia… - International journal of …, 2014 - Elsevier
Introduction Tablets are frequently subdivided to lower the dose, to facilitate swallowing by
eg children or older people or to save costs. Splitting devices are commonly used when …

Concerns regarding tablet splitting: a systematic review

AK Saran, NA Holden, SR Garrison - BJGP open, 2022 - bjgpopen.org
Background Tablet splitting can provide dose flexibility and cost savings; however,
pharmaceutical representatives typically discourage the practice. Aim To identify and …

Tablet splitting: is it worthwhile? Analysis of drug content and weight uniformity for half tablets of 16 commonly used medications in the outpatient setting

SA Helmy - Journal of managed care & specialty pharmacy, 2015 - jmcp.org
BACKGROUND: Tablet splitting is a well-established medical practice in clinical settings for
multiple reasons, including cost savings and ease of swallowing. However, it does not …

Performance of tablet splitters, crushers, and grinders in relation to personalised medication with tablets

HJ Woerdenbag, JC Visser, MPAM Leferink op Reinink… - Pharmaceutics, 2022 - mdpi.com
Swallowing problems and the required dose adaptations needed to obtain optimal
pharmacotherapy may be a hurdle in the use of tablets in daily clinical practice. Tablet …

Tablet splitting and weight uniformity of half-tablets of 4 medications in pharmacy practice

LM Tahaineh, SF Gharaibeh - Journal of Pharmacy Practice, 2012 - journals.sagepub.com
Background: Tablet splitting is a common practice for multiple reasons including cost
savings; however, it does not necessarily result in weight-uniform half-tablets. Objectives: To …

Fast assessment of the surface distribution of API and excipients in tablets using NIR-hyperspectral imaging

F Franch-Lage, JM Amigo, E Skibsted… - International journal of …, 2011 - Elsevier
The inclusion of hyperspectral imaging systems in the manufacturing and development of
pharmaceutical products is allowing a successful improvement in the quality control of solid …

Key technical aspects influencing the accuracy of tablet subdivision

MT Teixeira, LCL Sá-Barreto, T Gratieri, GM Gelfuso… - AAPS …, 2017 - Springer
Tablet subdivision is a common practice used mainly for dose adjustment. The aim of this
study was to investigate how the technical aspects of production as well as the method of …

A quality by design approach for the optimization of olmesartan medoxomil-orodispersible lyophilisates: in vitro/in vivo evaluation

SH Noshi, MHS Dawoud, MS Ibrahim - 2022 - repository.msa.edu.eg
The current study aims to develop orodispersible lyophilisates (ODLs), containing
olmesartan medoxomil (OLM), by applying a quality by design approach to ensure product …