Simple Summary For mammalian cells, glucose is a major source of energy. In the presence
of oxygen, a complete breakdown of glucose generates 36 molecules of ATP from one …

Mitochondria are essential cellular organelles that are involved in regulating cellular energy,
metabolism, survival, and proliferation. To some extent, cancer is a genetic and metabolic …

The number of diabetic patients has risen dramatically in recent decades, owing mostly to
the rising incidence of type 2 diabetes mellitus (T2DM). Several oral antidiabetic …

Background: The management of aggressive and progressive metastatic papillary thyroid
cancer (PTC) is very difficult. An inverse relationship between radioiodine and F-18 …

Background Therapeutic resistance to radiation and chemotherapy is one of the major
obstacles in cancer treatment. Although synthetic radiosensitizers are pragmatic solution to …

Like living organisms, cancer cells require energy to survive and interact with their
environment. Mitochondria are the main organelles for energy production and cellular …

Simple Summary Cancer represents unrestricted growth with the removal of conventional
brakes that control growth under normal conditions. This requires novel mechanisms to …

Glucose is an essential nutrient for every cell but its metabolic fate depends on cellular
phenotype. Normally, the product of cytosolic glycolysis, pyruvate, is transported into …

Simple Summary Radioiodine therapy is the main treatment option for metastatic
differentiated thyroid cancer (DTC). However, only half of these patients achieve (partial or …

The most serious hallmark step of carcinogenesis is oxidative stress, which induces cell
DNA damage. Although in normal conditions ROS are important second messengers, in …