Injuries to articular cartilage are one of the most challenging issues of musculoskeletal
medicine due to the poor intrinsic ability of this tissue for repair. The lack of efficient …

This review focuses on current tissue engineering strategies for promoting vascularized
bone regeneration. We review the role of angiogenic growth factors in promoting …

Abstract Three-dimensional (3D) protein-patterned scaffolds provide a more biomimetic
environment for cell culture than traditional two-dimensional surfaces, but simultaneous 3D …

The micro-environment in which stem cells reside regulates their fate, and synthetic
materials have recently been designed to emulate these regulatory processes for various …

Stem cells reside in adult and embryonic tissues in a broad spectrum of developmental
stages and lineages, and they are thus naturally exposed to diverse microenvironments or …

Bone is a highly vascularized organ, providing structural support to the body, and its
development, regeneration, and remodeling depend on the microvascular homeostasis …

Stem cell niche is a specialized and dynamic microenvironment around the stem cells which
plays a critical role in maintaining the stemness properties of stem cells. Over the years …

Background/Aims: Lithium chloride (LiCl) has long been used as a psychiatric medication;
however, its role in the differentiation of bone marrow-derived mesenchymal stem cells …

The goal of this project was to develop 3-D biomaterial scaffolds that present cues to direct
the differentiation of embryonic stem (ES) cell-derived neural progenitor cells, seeded inside …

Cartilage tissue engineering is an emerging technique for the regeneration of cartilage
tissue damaged as a result of trauma or disease. As the propensity for healing and …