The role of m6A modification in the biological functions and diseases
X Jiang, B Liu, Z Nie, L Duan, Q Xiong, Z Jin… - Signal transduction and …, 2021 - nature.com
Abstract N6-methyladenosine (m6A) is the most prevalent, abundant and conserved internal
cotranscriptional modification in eukaryotic RNAs, especially within higher eukaryotic cells …
cotranscriptional modification in eukaryotic RNAs, especially within higher eukaryotic cells …
The role of adult hippocampal neurogenesis in brain health and disease
Adult neurogenesis in the dentate gyrus of the hippocampus is highly regulated by a number
of environmental and cell-intrinsic factors to adapt to environmental changes. Accumulating …
of environmental and cell-intrinsic factors to adapt to environmental changes. Accumulating …
Exosome mediated delivery of miR-124 promotes neurogenesis after ischemia
J Yang, X Zhang, X Chen, L Wang, G Yang - Molecular Therapy-Nucleic …, 2017 - cell.com
The intrinsic ability of neurogenesis after stroke has been proven weak, which results in
insufficient repair of injury in the nerve system. Recent studies suggest multiple microRNAs …
insufficient repair of injury in the nerve system. Recent studies suggest multiple microRNAs …
Adult mammalian neural stem cells and neurogenesis: five decades later
Adult somatic stem cells in various organs maintain homeostatic tissue regeneration and
enhance plasticity. Since its initial discovery five decades ago, investigations of adult …
enhance plasticity. Since its initial discovery five decades ago, investigations of adult …
Adult neurogenesis in the mammalian brain: significant answers and significant questions
Adult neurogenesis, a process of generating functional neurons from adult neural
precursors, occurs throughout life in restricted brain regions in mammals. The past decade …
precursors, occurs throughout life in restricted brain regions in mammals. The past decade …
Adult neurogenesis contributes to hippocampal plasticity
Adult hippocampal neurogenesis is the process by which new functional neurons are added
to the adult dentate gyrus of the hippocampus. Animal studies have shown that the degree of …
to the adult dentate gyrus of the hippocampus. Animal studies have shown that the degree of …
Epigenetic mechanisms in neurogenesis
In the embryonic and adult brain, neural stem cells proliferate and give rise to neurons and
glia through highly regulated processes. Epigenetic mechanisms—including DNA and …
glia through highly regulated processes. Epigenetic mechanisms—including DNA and …
The epigenetics of aging and neurodegeneration
Epigenetics is a quickly growing field encompassing mechanisms regulating gene
expression that do not involve changes in the genotype. Epigenetics is of increasing …
expression that do not involve changes in the genotype. Epigenetics is of increasing …
Cell cycle regulation of stem cells by microRNAs
MMJ Mens, M Ghanbari - Stem cell reviews and reports, 2018 - Springer
MicroRNAs (miRNAs) are a class of small non-coding RNA molecules involved in the
regulation of gene expression. They are involved in the fine-tuning of fundamental biological …
regulation of gene expression. They are involved in the fine-tuning of fundamental biological …
MicroRNAs in neural development: from master regulators to fine-tuners
M Rajman, G Schratt - Development, 2017 - journals.biologists.com
The proper formation and function of neuronal networks is required for cognition and
behavior. Indeed, pathophysiological states that disrupt neuronal networks can lead to …
behavior. Indeed, pathophysiological states that disrupt neuronal networks can lead to …