Chronic pain is known to be caused by sensitization within the pain circuits. An imbalance
occurs between excitatory and inhibitory transmission that enables this sensitization to form …

The skeleton adapts to mechanical loading to promote bone formation and remodeling.
While most bone cells are involved in mechanosensing, it is well accepted that osteocytes …

Mechanisms resulting in abdominal pain include altered neuro-immune interactions in the
gastrointestinal tract, but the signaling processes that link immune activation with visceral …

Satellite glial cells (SGCs) are among the most abundant non-neuronal cells in dorsal root
ganglia (DRGs) and closely envelop sensory neurons that detect painful stimuli. However …

Diverse specialised neuroglial cells guarantee the development, preservation, and health of
the central nervous system, the peripheral nervous system, the enteric nervous system, and …

Spontaneous Ca2+ transients of neural cells is a hallmark of the developing nervous
system. It is widely accepted that chemical signals, like neurotransmitters, contribute to …

Pain is a physiological response to bodily damage and serves as a warning of potential
threat. Pain can also transform from an acute response to noxious stimuli to a chronic …

Pannexins belong to a family of ATP-release channels expressed in almost all cell types. An
increasing body of literature on pannexins suggests that these channels play dual and …

Fucoxanthin is a carotenoid with many pharmaceutical properties that is found in brown
seaweed. However, the effects of fucoxanthin on corneal innervation and intense eye pain …

Satellite glial cells surround neurons within dorsal root ganglia. Previous studies have
focused on single-cell suspensions of cultured neurons derived from rat dorsal root ganglia …