Noncoding RNAs: the shot callers in tumor immune escape

L Liu, Q Wang, Z Qiu, Y Kang, J Liu, S Ning… - Signal transduction and …, 2020 - nature.com
Immunotherapy, designed to exploit the functions of the host immune system against tumors,
has shown considerable potential against several malignancies. However, the utility of …

Immune response and immune checkpoint molecules in patients with rectal cancer undergoing neoadjuvant chemoradiotherapy: a review

IM Koukourakis, K Platoni, D Tiniakos… - Current Issues in …, 2023 - mdpi.com
It is well-established that tumor antigens and molecules expressed and secreted by cancer
cells trigger innate and adaptive immune responses. These two types of anti-tumor immunity …

[HTML][HTML] Synergistic killing effects of PD-L1-CAR T cells and colorectal cancer stem cell-dendritic cell vaccine-sensitized T cells in ALDH1-positive colorectal cancer …

L Liu, Y Liu, Y Xia, G Wang, X Zhang, H Zhang… - Journal of …, 2021 - ncbi.nlm.nih.gov
Cancer stem cells (CSCs) are characterized by self-renewal and unlimited proliferation,
providing a basis for tumor occurrence, metastasis, and recurrence. Because CSCs are …

Epithelial-mesenchymal transition-related microRNAs and their target genes in colorectal cancerogenesis

B Ranković, N Zidar, M Žlajpah… - Journal of clinical medicine, 2019 - mdpi.com
MicroRNAs of the miR-200 family have been shown experimentally to regulate epithelial-
mesenchymal transition (EMT). Although EMT is the postulated mechanism of development …

Bioinformatics analysis of RNA-seq data reveals genes related to cancer stem cells in colorectal cancerogenesis

K Urh, N Zidar, E Boštjančič - International Journal of Molecular Sciences, 2022 - mdpi.com
Cancer stem cells (CSC) play one of the crucial roles in the pathogenesis of various
cancers, including colorectal cancer (CRC). Although great efforts have been made …

High density of cytotoxic T-lymphocytes is linked to tumoral PD-L1 expression regardless of the mismatch repair status in colorectal cancer

K Möller, NC Blessin, D Höflmayer, F Büscheck… - Acta …, 2021 - Taylor & Francis
Background Immune checkpoint-inhibitors targeting the PD-1/PD-L1 system are FDA
approved in microsatellite instable (MSI) or mismatch repair deficient (dMMR) colorectal …

Evaluation of immunohistochemical markers, CK17 and SOX2, as adjuncts to p53 for the diagnosis of differentiated vulvar intraepithelial neoplasia (dVIN)

S Dasgupta, S Koljenović, TPP van den Bosch… - Pharmaceuticals, 2021 - mdpi.com
Histological diagnosis of differentiated vulvar intraepithelial neoplasia (dVIN), the precursor
of human papillomavirus (HPV)-independent vulvar squamous cell carcinoma (VSCC), can …

[HTML][HTML] The role and relationship between programmed death ligand 1 and cytotoxic T lymphocyte-associated antigen-4 immunohistochemical expression in …

ASED Mohameda, HS El-Rebey… - …, 2021 - ncbi.nlm.nih.gov
Background Globally, colorectal carcinoma (CRC) is the third most common cancer
diagnosed in both men and women. Programmed death ligand 1 (PD-L1) and cytotoxic T …

The role and relationship between programmed death ligand 1 and cytotoxic T lymphocyte-associated antigen-4 immunohistochemical expression in colorectal …

HS El-Rebey, AELS Abdelsamed… - …, 2021 - search.proquest.com
Background Globally, colorectal carcinoma (CRC) is the third most common cancer
diagnosed in both men and women. Programmed death ligand 1 (PD-L1) and cytotoxic T …

SOX2 影响PD-L1 表达参与乳腺癌细胞免疫逃逸的机制探讨.

张小燕, 尚红梅, 汪丹丹, 陈芳… - Progress in Modern …, 2024 - search.ebscohost.com
摘要目的: 探讨转录因子性别决定区Y 框蛋白2 (SOX2) 基因通过诱导程序性死亡因子配体1 (PD-
L1) 表达, 促进乳腺癌细胞免疫逃逸的作用机制. 方法: qRT-PCR 和Western blot …