Engineered receptors for soluble cell-to-cell communication

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Designed endocytosis-inducing proteins degrade targets and amplify signals

B Huang, M Abedi, G Ahn, B Coventry, I Sappington… - Nature, 2024 - nature.com
Endocytosis and lysosomal trafficking of cell surface receptors can be triggered by
endogenous ligands. Therapeutic approaches such as lysosome-targeting …
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