Reappraising the role of inflammation in heart failure

L Adamo, C Rocha-Resende, SD Prabhu… - Nature Reviews …, 2020 - nature.com
The observation that heart failure with reduced ejection fraction is associated with elevated
circulating levels of pro-inflammatory cytokines opened a new area of research that has …

Somatosensory and autonomic neuronal regulation of the immune response

S Udit, K Blake, IM Chiu - Nature Reviews Neuroscience, 2022 - nature.com
Bidirectional communication between the peripheral nervous system (PNS) and the immune
system is a crucial part of an effective but balanced mammalian response to invading …

[HTML][HTML] Somatotopic organization and intensity dependence in driving distinct NPY-expressing sympathetic pathways by electroacupuncture

S Liu, ZF Wang, YS Su, RS Ray, XH Jing, YQ Wang… - Neuron, 2020 - cell.com
The neuroanatomical basis behind acupuncture practice is still poorly understood. Here, we
used intersectional genetic strategy to ablate NPY+ noradrenergic neurons and/or adrenal …

Central glucagon-like peptide 1 receptor activation inhibits Toll-like receptor agonist-induced inflammation

CK Wong, BA McLean, LL Baggio, JA Koehler… - Cell Metabolism, 2024 - cell.com
Glucagon-like peptide-1 receptor agonists (GLP-1RAs) exert anti-inflammatory effects
relevant to the chronic complications of type 2 diabetes. Although GLP-1RAs attenuate T cell …

Effects of exercise training on the autonomic nervous system with a focus on anti-inflammatory and antioxidants effects

M Daniela, L Catalina, O Ilie, M Paula, I Daniel-Andrei… - Antioxidants, 2022 - mdpi.com
Studies show that the autonomic nervous system (ANS) has an important impact on health in
general. In response to environmental demands, homeostatic processes are often …

Advances in the understanding and treatment of sepsis-induced immunosuppression

F Venet, G Monneret - Nature Reviews Nephrology, 2018 - nature.com
Sepsis is defined as a life-threatening organ dysfunction that is caused by a dysregulated
host response to infection. Sepsis can induce acute kidney injury and multiple organ failures …

Heart rate variability and inflammation: a meta-analysis of human studies

DWP Williams, J Koenig, L Carnevali, A Sgoifo… - Brain, behavior, and …, 2019 - Elsevier
The inflammatory reflex is known as the body's primary defense against infection and has
been implicated in a number of diseases. The magnitude of the inflammatory response is …

Sepsis therapies: learning from 30 years of failure of translational research to propose new leads

JM Cavaillon, M Singer, T Skirecki - EMBO molecular medicine, 2020 - embopress.org
Sepsis has been identified by the World Health Organization (WHO) as a global health
priority. There has been a tremendous effort to decipher underlying mechanisms …

Breath of life: the respiratory vagal stimulation model of contemplative activity

RJS Gerritsen, GPH Band - Frontiers in human neuroscience, 2018 - frontiersin.org
Contemplative practices, such as meditation and yoga, are increasingly popular among the
general public and as topics of research. Beneficial effects associated with these practices …

Neuroimmune interactions in peripheral organs

RGJ Klein Wolterink, GS Wu, IM Chiu… - Annual review of …, 2022 - annualreviews.org
Interactions between the nervous and immune systems were recognized long ago, but
recent studies show that this crosstalk occurs more frequently than was previously …