Reactive nitrogen species include nitric oxide (· NO), peroxynitrite (ONOO−) and nitrogen
dioxide radical (NO2·). Peroxynitrite is a reactive oxidant, produced from nitric oxide (· NO) …

Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease
characterized by autoantibodies directed against various biomolecules. The initial …

Background Leishmaniasis is a parasitic infection endemic in more than ninety countries of
the world. The cutaneous leishmaniasis (CL) is a most common form of leishmaniasis and it …

Anti-DNA antibodies are now considered as a universal diagnostic feature for the patients
with systemic lupus erythematosus (SLE) but the mechanism (s) involved in the generation …

Background: Peroxynitrite (ONOO−) is an oxidant linked with several human pathologies.
Apigenin, a natural flavonoid known for its health benefits, remains unexplored in relation to …

Peroxynitrite is a potent oxidizing and nitrating agent which has detrimental effects on cells
by altering the structure and function of biomolecules present within. A fluorescent probe …

Peroxynitrite (ONOO−) is a reactive oxidant involved in numerous pathological conditions.
Thymoquinone (TQ) is an active constituent of Nigella sativa and is reported to have anti …

Peroxynitrite is a member of reactive nitrogen species that also includes nitric oxide (· NO)
and nitrogen dioxide radical (NO2·). Peroxynitrite is a reactive nitrogen species and an …

Peroxynitrite is known to react with biomolecules leading to their structural and function
alteration. Structural alteration in DNA induced by peroxynitrite is not clearly known. The …

Objectives Peroxynitrite interacts with biomolecules through oxidative reactions or radical-
mediated mechanisms leading to oxidative damage and committing cells to necrosis or/and …