Helminth parasites are masters at manipulating host immune responses, using an array of
sophisticated mechanisms. One of the major mechanisms enabling helminths to establish …

Fructose 1, 6-bisphosphate aldolase is a ubiquitous cytosolic enzyme that catalyzes the
fourth step of glycolysis. Aldolases are classified into three groups: Class-I, Class-IA, and …

Helminth parasites secrete extracellular vesicles (EVs) that can be internalised by host
immune cells resulting in modulation of host immunity. While the molecular cargo of EVs …

Parasite-released extracellular vesicles (EVs) deliver signals to the host immune system that
are critical to maintaining the long-term relationship between parasite and host. In the …

Fasciolosis caused by trematode parasites of the genus Fasciola is a global disease of
livestock, particularly cattle, sheep, water buffalo and goats. It is also a major human …

Unraveling the molecular interactions governing the first contact between parasite and host
tissues is of paramount importance to the development of effective control strategies against …

Background The tropical liver fluke, Fasciola gigantica causes fasciolosis, an important
disease of humans and livestock. We characterized dynamic transcriptional changes …

In the past decade significant advances in our understanding of liver fluke biology have
been made through in-depth interrogation and analysis of evolving Fasciola hepatica and …

The liver fluke Fasciola hepatica is an economically important pathogen of livestock
worldwide, as well as being an important neglected zoonosis. Parasite control is reliant on …

Fasciola hepatica is a trematode parasite distributed worldwide. It is known to cause disease
in mammals, producing significant economic loses to livestock industry and burden to …