Clinical and economic consequences of ventilator-associated pneumonia: a systematic review

N Safdar, C Dezfulian, HR Collard… - Critical care medicine, 2005 - journals.lww.com
Background: Ventilator-associated pneumonia (VAP) is the most common nosocomial
infection in critically ill patients. The clinical and economic consequences of VAP are …

Association between selective decontamination of the digestive tract and in-hospital mortality in intensive care unit patients receiving mechanical ventilation: a …

NE Hammond, J Myburgh, I Seppelt, T Garside, R Vlok… - Jama, 2022 - jamanetwork.com
Importance The effectiveness of selective decontamination of the digestive tract (SDD) in
critically ill adults receiving mechanical ventilation is uncertain. Objective To determine …

[HTML][HTML] Guidelines for preventing healthcare-associated pneumonia, 2003

OC Tablan, LJ Anderson, R Besser, C Bridges… - MMWR, 2004 - cdc.gov
This report updates, expands, and replaces the previously published CDC" Guideline for
Prevention of Nosocomial Pneumonia". The new guidelines are designed to reduce the …

Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis

D Bassler, M Briel, VM Montori, M Lane, P Glasziou… - Jama, 2010 - jamanetwork.com
Context Theory and simulation suggest that randomized controlled trials (RCTs) stopped
early for benefit (truncated RCTs) systematically overestimate treatment effects for the …

Decontamination of the digestive tract and oropharynx in ICU patients

A De Smet, J Kluytmans, BS Cooper… - … England Journal of …, 2009 - Mass Medical Soc
Background Selective digestive tract decontamination (SDD) and selective oropharyngeal
decontamination (SOD) are infection-prevention measures used in the treatment of some …

Selective digestive or oropharyngeal decontamination and topical oropharyngeal chlorhexidine for prevention of death in general intensive care: systematic review …

R Price, G MacLennan, J Glen - Bmj, 2014 - bmj.com
Objectives To determine the effect on mortality of selective digestive decontamination,
selective oropharyngeal decontamination, and topical oropharyngeal chlorhexidine in adult …

Multiple organ failure syndrome in the 1990s: systemic inflammatory response and organ dysfunction

AL Beal, FB Cerra - Jama, 1994 - jamanetwork.com
Objective.—This review of the systemic inflammatory response syndrome (SIRS) and
multiple organ dysfunction syndrome (MODS) provides an overview of a common but …

Effects of selective decontamination of digestive tract on mortality and acquisition of resistant bacteria in intensive care: a randomised controlled trial

E de Jonge, MJ Schultz, L Spanjaard, PMM Bossuyt… - The Lancet, 2003 - thelancet.com
Background Selective decontamination of the digestive tract (SDD) is an infection-
prevention regimen used in critically ill patients. We assessed the effects of SDD on …

Chlorhexidine gluconate 0.12% oral rinse reduces the incidence of total nosocomial respiratory infection and nonprophylactic systemic antibiotic use in patients …

AJ DeRiso II, JS Ladowski, TA Dillon, JW Justice… - Chest, 1996 - Elsevier
Study objective The purpose of this study was to test the effectiveness of oropharyngeal
decontamination on nosocomial infections in a comparatively homogeneous population of …

Antibiotic prophylaxis to reduce respiratory tract infections and mortality in adults receiving intensive care

R D'Amico, S Pifferi, V Torri, L Brazzi… - Cochrane Database …, 2009 - cochranelibrary.com
Background Pneumonia is an important cause of mortality in intensive care units (ICUs). The
incidence of pneumonia in ICU patients ranges between 7% and 40%, and the crude …