Atomic-resolution structural studies of membrane-associated proteins and peptides in a
membrane environment are important to fully understand their biological function and the …

G protein-coupled receptors (GPCRs), as the largest family of membrane receptors, actively
modulate plasma membrane and endosomal signalling. Importantly, GPCRs are naturally …

Amphiphilic copolymers consisting of alternating hydrophilic and hydrophobic units account
for a major recent methodical breakthrough in the investigations of membrane proteins …

Complex integral membrane proteins, which are embedded in the cell surface lipid bilayer
by multiple transmembrane spanning polypeptides, encompass families of proteins that are …

G-protein-coupled receptors (GPCRs) are the largest family of membrane proteins, regulate
a plethora of physiological responses and are the therapeutic target for 30–40% of clinically …

Microfluidic diffusional sizing (MDS) is a recent and powerful method for determining the
hydrodynamic sizes and interactions of biomolecules and nanoparticles. A major benefit of …

G protein-coupled receptors (GPCRs) are an important family of membrane proteins
responsible for many physiological functions in human body. High resolution GPCR …

The human neurotensin receptor one (NTSR1) is a G protein-coupled receptor. The receptor
is activated by a small peptide ligand neurotensin. NTSR1 can be expressed in HEK cells by …

G protein-coupled receptors (GPCRs) are membrane proteins that transmit specific external
stimuli into cells by changing their conformation. This conformational change allows them to …

Although membrane proteins are abundant in nature, their investigation is limited due to
bottlenecks in heterologous overexpression and consequently restricted accessibility for …