Photoinduced electron transfer (PeT) based fluorescent probes for cellular imaging and disease therapy

H Niu, J Liu, HM O'Connor, T Gunnlaugsson… - Chemical Society …, 2023 - pubs.rsc.org
Typical PeT-based fluorescent probes are multi-component systems where a fluorophore is
connected to a recognition/activating group by an unconjugated linker. PeT-based …

Fluorescent probes for sensing and imaging within specific cellular organelles

H Zhu, J Fan, J Du, X Peng - Accounts of chemical research, 2016 - ACS Publications
Conspectus Fluorescent probes have become powerful tools in biosensing and bioimaging
because of their high sensitivity, specificity, fast response, and technical simplicity. In the last …

[HTML][HTML] The role of NADPH oxidases in infectious and inflammatory diseases

JP Taylor, MT Hubert - Redox biology, 2021 - Elsevier
Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOX) are enzymes that
generate superoxide or hydrogen peroxide from molecular oxygen utilizing NADPH as an …

Heat stroke in cell tissues related to sulfur dioxide level is precisely monitored by light-controlled fluorescent probes

W Zhang, F Huo, Y Yue, Y Zhang, J Chao… - Journal of the …, 2020 - ACS Publications
Heat stroke (HS) can cause serious organism damage or even death. Early understanding
of the mechanism of heat cytotoxicity can prevent or treat heat stroke related diseases. In this …

Cysteine cathepsins in tumor-associated immune cells

T Jakoš, A Pišlar, A Jewett, J Kos - Frontiers in immunology, 2019 - frontiersin.org
Cysteine cathepsins are key regulators of the innate and adaptive arms of the immune
system. Their expression, activity, and subcellular localization are associated with the …

Lysosome targeting carbon dots-based fluorescent probe for monitoring pH changes in vitro and in vivo

P Gao, J Wang, M Zheng, Z Xie - Chemical Engineering Journal, 2020 - Elsevier
The anomalous fluctuations of pH in lysosome will cause the disorder of normal activity of
cells and even many diseases. Thus, developing a convenient strategy for tracking pH …

Nanogels for intracellular delivery of biotherapeutics

D Li, CF van Nostrum, E Mastrobattista… - Journal of Controlled …, 2017 - Elsevier
Many biomolecules, such as proteins and genes, are presently used as therapeutics.
However, their delivery to target sites inside cells is challenging because of their large …

A Lysosome-Targetable Fluorescent Probe for Simultaneously Sensing Cys/Hcy, GSH, and H2S from Different Signal Patterns

H Zhang, L Xu, W Chen, J Huang, C Huang… - ACS …, 2018 - ACS Publications
Biothiols, a vital branch of reactive sulfur species (RSS) family, are indispensable in human
physiology. However, the exact functional roles of each biothiol involved in complicated …

Application of multifunctional small molecule fluorescent probe BODIPY in life science

L Yuan, Y Su, H Cong, B Yu, Y Shen - Dyes and Pigments, 2023 - Elsevier
BODIPY and its derivative multifunctional small molecule probes have become the darlings
in the field of biomedical materials due to its unique molecular structure, high brightness …

Ncf1 polymorphism reveals oxidative regulation of autoimmune chronic inflammation

R Holmdahl, O Sareila, LM Olsson… - Immunological …, 2016 - Wiley Online Library
The current review on the function of neutrophil cytosolic factor 1 (NCF1) and induced
reactive oxygen species (ROS) is based on a genetic search for the major genes controlling …