[HTML][HTML] The global phosphorylation landscape of SARS-CoV-2 infection

M Bouhaddou, D Memon, B Meyer, KM White… - Cell, 2020 - cell.com
The causative agent of the coronavirus disease 2019 (COVID-19) pandemic, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected millions and killed …

When the good go bad: mutant NPM1 in acute myeloid leukemia

P Kunchala, S Kuravi, R Jensen, J McGuirk, R Balusu - Blood reviews, 2018 - Elsevier
Abstract Nucleophosmin 1 (NPM1) is a nucleolar phosphoprotein that performs diverse
biological functions including molecular chaperoning, ribosome biogenesis, DNA repair …

[HTML][HTML] Nucleophosmin in its interaction with ligands

I Cela, A Di Matteo, L Federici - International journal of molecular sciences, 2020 - mdpi.com
Nucleophosmin (NPM1) is a mainly nucleolar protein that shuttles between nucleoli,
nucleoplasm and cytoplasm to fulfill its many functions. It is a chaperone of both nucleic …

The role of the nucleolus in regulating the cell cycle and the DNA damage response

D Sakthivel, A Brown-Suedel… - Advances in Protein …, 2023 - Elsevier
The nucleolus has long been perceived as the site for ribosome biogenesis, but numerous
studies suggest that the nucleolus carefully sequesters crucial proteins involved in multiple …

Glycogen synthase kinase‐3 and alternative splicing

X Liu, PS Klein - Wiley Interdisciplinary Reviews: RNA, 2018 - Wiley Online Library
Glycogen synthase kinase‐3 (GSK‐3) is a highly conserved negative regulator of receptor
tyrosine kinase, cytokine, and Wnt signaling pathways. Stimulation of these pathways …

CK1 and PP1 regulate Rift Valley fever virus genome replication through L protein phosphorylation

N Bracci, A Baer, R Flor, K Petraccione, T Stocker… - Antiviral Research, 2024 - Elsevier
Rift Valley fever virus (RVFV) is an arbovirus in the Phenuiviridae family identified initially by
the large 'abortion storms' observed among ruminants; RVFV can also infect humans. In …

Oncogene c‐fos and mutant R175H p53 regulate expression of Nucleophosmin implicating cancer manifestation

P Senapati, S Dey, D Sudarshan, S Das… - The FEBS …, 2018 - Wiley Online Library
Nucleophosmin (NPM 1) is a nucleolar protein that is frequently overexpressed in various
types of solid tumors. NPM 1 is involved in several cellular processes that might contribute …

[HTML][HTML] Targeting the NAT10/NPM1 axis abrogates PD-L1 expression and improves the response to immune checkpoint blockade therapy

G Qin, F Bai, H Hu, J Zhang, W Zhan, Z Wu, J Li, Y Fu… - Molecular …, 2024 - Springer
Abstract Background PD-1/PD-L1 play a crucial role as immune checkpoint inhibitors in
various types of cancer. Although our previous study revealed that NPM1 was a novel …

Nucleophosmin in leukemia: consequences of anchor loss

B Brodská, M Šašinková, K Kuželová - … journal of biochemistry & cell biology, 2019 - Elsevier
Nucleophosmin (NPM), one of the most abundant nucleolar proteins, has crucial functions in
ribosome biogenesis, cell cycle control, and DNA-damage repair. In human cells, NPM …

[HTML][HTML] HIV-1 Transcription Inhibitor 1E7-03 Decreases Nucleophosmin Phosphorylation

X Lin, A Ahmad, AI Ivanov, J Simhadri, S Wang… - Molecular & Cellular …, 2023 - ASBMB
Transcription activation of latent human immunodeficiency virus-1 (HIV-1) occurs due to HIV-
1 rebound, the interruption of combination antiretroviral therapy, or development of drug …