[PDF][PDF] Induction and application of human naive pluripotency
J Zhou, J Hu, Y Wang, S Gao - Cell Reports, 2023 - cell.com
Over the past few decades, many attempts have been made to capture different states of
pluripotency in vitro. Naive and primed pluripotent stem cells, corresponding to the …
pluripotency in vitro. Naive and primed pluripotent stem cells, corresponding to the …
Integrating spatial and single-cell transcriptomics data using deep generative models with SpatialScope
The rapid emergence of spatial transcriptomics (ST) technologies is revolutionizing our
understanding of tissue spatial architecture and biology. Although current ST methods …
understanding of tissue spatial architecture and biology. Although current ST methods …
Advanced Cellular Models for Rare Disease Study: Exploring Neural, Muscle and Skeletal Organoids
C Bombieri, A Corsi, E Trabetti, A Ruggiero… - International journal of …, 2024 - mdpi.com
Organoids are self-organized, three-dimensional structures derived from stem cells that can
mimic the structure and physiology of human organs. Patient-specific induced pluripotent …
mimic the structure and physiology of human organs. Patient-specific induced pluripotent …
PD-L1 regulates inflammatory programs of macrophages from human pluripotent stem cells
H Cao, Y Xiang, S Zhang, Y Chao, J Guo… - Life Science …, 2024 - life-science-alliance.org
Programmed death ligand 1 (PD-L1) serves as a pivotal immune checkpoint in both the
innate and adaptive immune systems. PD-L1 is expressed in macrophages in response to …
innate and adaptive immune systems. PD-L1 is expressed in macrophages in response to …
SARS-CoV-2 infection activates inflammatory macrophages in vascular immune organoids
CW Chau, A To, RKH Au-Yeung, K Tang, Y Xiang… - Scientific Reports, 2024 - nature.com
SARS-CoV-2 provokes devastating tissue damage by cytokine release syndrome and leads
to multi-organ failure. Modeling the process of immune cell activation and subsequent tissue …
to multi-organ failure. Modeling the process of immune cell activation and subsequent tissue …
PD-L1 regulates inflammatory macrophage development from human pluripotent stem cells by maintaining interferon-gamma signal
Abstract PD-L1 (programmed death-ligand 1) serves as a pivotal immune checkpoint in both
the innate and adaptive immune systems. PD-L1 is expressed in macrophages in response …
the innate and adaptive immune systems. PD-L1 is expressed in macrophages in response …
SpatialScope: A unified approach for integrating spatial and single-cell transcriptomics data using deep generative models
The rapid emergence of spatial transcriptomics (ST) technologies are revolutionizing our
under-standing of tissue spatial architecture and their biology. Current ST technologies …
under-standing of tissue spatial architecture and their biology. Current ST technologies …
Single-cell mitochondrial variant enrichment resolved clonal tracking and spatial architecture in human embryonic hematopoiesis
The ability to perform lineage tracing at the single-cell level is critical to reconstructing
dynamic transitions during cell differentiation. However, prospective tracing approaches …
dynamic transitions during cell differentiation. However, prospective tracing approaches …