NADPH P450 oxidoreductase: structure, function, and pathology of diseases
Cytochrome P450 oxidoreductase (POR) is an enzyme that is essential for multiple
metabolic processes, chiefly among them are reactions catalyzed by cytochrome P450 …
metabolic processes, chiefly among them are reactions catalyzed by cytochrome P450 …
The pharmacology of the cytochrome P450 epoxygenase/soluble epoxide hydrolase axis in the vasculature and cardiovascular disease
I Fleming - Pharmacological reviews, 2014 - ASPET
Over the last 20 years, it has become clear that cytochrome P450 (P450) enzymes generate
a spectrum of bioactive lipid mediators from endogenous substrates. However, studies …
a spectrum of bioactive lipid mediators from endogenous substrates. However, studies …
[HTML][HTML] Gap junctions and hemichannels in signal transmission, function and development of bone
N Batra, R Kar, JX Jiang - Biochimica et Biophysica Acta (BBA) …, 2012 - Elsevier
Gap junctional intercellular communication (GJIC) mediated by connexins, in particular
connexin 43 (Cx43), plays important roles in regulating signal transmission among different …
connexin 43 (Cx43), plays important roles in regulating signal transmission among different …
The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication
A Fumagalli, J Heuninck, A Pizzoccaro… - Nature …, 2020 - nature.com
The atypical chemokine receptor 3 (ACKR3) plays a pivotal role in directing the migration of
various cellular populations and its over-expression in tumors promotes cell proliferation …
various cellular populations and its over-expression in tumors promotes cell proliferation …
Identification of crucial genes and infiltrating immune cells underlying sepsis-induced cardiomyopathy via weighted gene Co-expression network analysis
J Li, L Zhou, Z Li, S Yang, L Tang, H Gong - Frontiers in Genetics, 2021 - frontiersin.org
Sepsis-induced cardiomyopathy (SIC), with a possibly reversible cardiac dysfunction, is a
potential complication of septic shock. Despite quite a few mechanisms including the …
potential complication of septic shock. Despite quite a few mechanisms including the …
Genistein targets STING-driven antiviral responses
TR Ullah, KR Balka, RL Ambrose, G Pépin, MCJ Wilce… - MBio, 2022 - Am Soc Microbiol
Cytoplasmic detection of DNA by cyclic GMP-AMP (cGAMP) synthase (cGAS) is an essential
component of antiviral responses. Upon synthesis, cGAMP binds to the stimulator of …
component of antiviral responses. Upon synthesis, cGAMP binds to the stimulator of …
Carbon monoxide-releasing molecule-2 inhibits connexin 43-hemichannel activity in spinal cord astrocytes to attenuate neuropathic pain
H Wang, X Sun - Journal of Molecular Neuroscience, 2017 - Springer
Carbon monoxide-releasing molecule (CORM-2) acts as a carbon monoxide (CO) deliverer
in a more controlled manner without altering carboxyhemoglobin level and exerts potential …
in a more controlled manner without altering carboxyhemoglobin level and exerts potential …
[HTML][HTML] 46, XX DSD and Antley-Bixler syndrome due to novel mutations in the cytochrome P450 oxidoreductase gene
G Guaragna-Filho, CCTS Castro… - … de Endocrinologia & …, 2012 - SciELO Brasil
Deficiency of the enzyme P450 oxidoreductase is a rare form of congenital adrenal
hyperplasia with characteristics of combined and partial impairments in steroidogenic …
hyperplasia with characteristics of combined and partial impairments in steroidogenic …
Conditional deletion of cytochrome p450 reductase in osteoprogenitor cells affects long bone and skull development in mice recapitulating antley-bixler syndrome …
NADPH-cytochrome P450 oxidoreductase (POR) is the primary electron donor for
cytochromes P450, dehydrocholesterol reductase, heme oxygenase, and squalene …
cytochromes P450, dehydrocholesterol reductase, heme oxygenase, and squalene …
P450 oxidoreductase deficiency
Cytochrome P450 oxidoreductase (POR) is an enzyme that is essential for multiple
metabolic processes; chiefly among them are reactions catalyzed by cytochrome P450 …
metabolic processes; chiefly among them are reactions catalyzed by cytochrome P450 …