[HTML][HTML] Montelukast drug may improve COVID-19 prognosis: a review of evidence
J Barré, JM Sabatier, C Annweiler - Frontiers in pharmacology, 2020 - frontiersin.org
With the lack of effective therapy, chemoprevention and vaccination, focusing on the
immediate repurposing of existing drugs gives hope of curbing the pandemic. Interestingly …
immediate repurposing of existing drugs gives hope of curbing the pandemic. Interestingly …
The leukotriene receptor antagonist montelukast and its possible role in the cardiovascular field
Abstract Background Cysteinyl leukotrienes (LTC4, LTD4, and LTE4) are pro-inflammatory
mediators of the 5-lipooxygenase (5-LO) pathway, that play an important role in …
mediators of the 5-lipooxygenase (5-LO) pathway, that play an important role in …
Atorvastatin-mediated downregulation of VCAM-1 and XO/UA/caspase 3 signaling averts oxidative damage and apoptosis induced by ovarian ischaemia/reperfusion …
Background Oxidative damage is critical in the pathogenesis of ovarian
ischaemia/reperfusion (I/R) injury, and statins have been reported to exert antioxidant …
ischaemia/reperfusion (I/R) injury, and statins have been reported to exert antioxidant …
Montelukast attenuates rotenone-induced microglial activation/p38 MAPK expression in rats: Possible role of its antioxidant, anti-inflammatory and antiapoptotic effects
RM Mansour, MAE Ahmed, AE El-Sahar… - Toxicology and applied …, 2018 - Elsevier
Montelukast (MK), a cysteinyl leukotriene (CysLT1) receptor antagonist, latterly exhibited a
remarkable neuroprotective activity in various neurodegenerative disorders. This study aims …
remarkable neuroprotective activity in various neurodegenerative disorders. This study aims …
Aliskiren–a promising strategy for ovarian ischemia/reperfusion injury protection in rats via RAAS
The aim of this study was to evaluate the effects of aliskiren, direct renin inhibitor, as an
antioxidant and tissue protective agent and evaluate the molecular, biochemical, and …
antioxidant and tissue protective agent and evaluate the molecular, biochemical, and …
Protective effects of esculetin against ovary ischemia–reperfusion injury model in rats
Aims Ovarian ischemia–reperfusion (I/R) injury is a phenomenon that necessitates urgent
intervention, which occurs as a result of ovarian torsion, and it is frequently seen in young …
intervention, which occurs as a result of ovarian torsion, and it is frequently seen in young …
Growth hormone reduces tissue damage in rat ovaries subjected to torsion and detorsion: biochemical and histopathologic evaluation
OBJECTIVE: To evaluate the effects of growth hormone (GH) as an antioxidant and tissue-
protective agent and analyse the biochemical and histopathological changes in rat ovaries …
protective agent and analyse the biochemical and histopathological changes in rat ovaries …
The effect of levosimendan in rat mesenteric ischemia/reperfusion injury
Background: Intestinal ischemia reperfusion (IR) is associated with morbidity and mortality.
We first examined the role of levosimendan in the protection of intestine after mesenteric IR …
We first examined the role of levosimendan in the protection of intestine after mesenteric IR …
The effect of edaravone on ischemia–reperfusion injury in rat ovary
OBJECTIVE: The aim of this study was to investigate the effect of edaravone on
experimentally induced ovarian torsion/detorsion ischemia/reperfusion (I/R) injury. STUDY …
experimentally induced ovarian torsion/detorsion ischemia/reperfusion (I/R) injury. STUDY …
Protective effect of oxytocin on ovarian ischemia-reperfusion injury in rats
Oxytocin (OT), a neurohypophysial nonapeptide, plays dual role as a neurotransmitter/
neuromodulator and a hormone. It has also well known protective properties against …
neuromodulator and a hormone. It has also well known protective properties against …