[HTML][HTML] The function of N-myc downstream-regulated gene 2 (NDRG2) as a negative regulator in tumor cell metastasis
KW Lee, S Lim, KD Kim - International Journal of Molecular Sciences, 2022 - mdpi.com
N-myc downstream-regulated gene 2 (NDRG2) is a tumor-suppressor gene that suppresses
tumorigenesis and metastasis of tumors and increases sensitivity to anti-cancer drugs. In this …
tumorigenesis and metastasis of tumors and increases sensitivity to anti-cancer drugs. In this …
[HTML][HTML] Emerging role of N-myc downstream-regulated gene 2 (NDRG2) in cancer
W Hu, C Fan, P Jiang, Z Ma, X Yan, S Di, S Jiang… - …, 2015 - pmc.ncbi.nlm.nih.gov
N-myc downstream-regulated gene 2 (NDRG2) is a tumor suppressor and cell stress-related
gene. NDRG2 is associated with tumor incidence, progression, and metastasis. NDRG2 …
gene. NDRG2 is associated with tumor incidence, progression, and metastasis. NDRG2 …
Loss of NDRG2 promotes epithelial-mesenchymal transition of gallbladder carcinoma cells through MMP-19-mediated Slug expression
DG Lee, SH Lee, JS Kim, J Park, YL Cho, KS Kim… - Journal of …, 2015 - Elsevier
Background & Aims Gallbladder carcinoma (GBC) is the most common malignancy of the
biliary tract and one of the most lethal forms of human cancer. However, there is limited …
biliary tract and one of the most lethal forms of human cancer. However, there is limited …
Clinical and pathological significance of N-Myc downstream-regulated gene 2 (NDRG2) in diverse human cancers
W Hu, Y Yang, C Fan, Z Ma, C Deng, T Li, J Lv, W Yao… - Apoptosis, 2016 - Springer
Human N-Myc downstream-regulated gene 2 (NDRG2), located at chromosome 14q11. 2,
has been reported to be down-regulated and associated with the progression and prognosis …
has been reported to be down-regulated and associated with the progression and prognosis …
[HTML][HTML] NDRG2 expression in breast cancer cells downregulates PD-L1 expression and restores T cell proliferation in tumor-coculture
A Lee, S Lim, J Oh, J Lim, Y Yang, MS Lee, JS Lim - Cancers, 2021 - mdpi.com
Simple Summary N-myc downstream-regulated gene 2 (NDRG2) is a candidate tumor
suppressor in various cancers, including breast cancer. Increased expression of …
suppressor in various cancers, including breast cancer. Increased expression of …
[HTML][HTML] Potential role of the N-MYC downstream-regulated gene family in reprogramming cancer metabolism under hypoxia
GY Lee, YS Chun, HW Shin, JW Park - Oncotarget, 2016 - ncbi.nlm.nih.gov
Metabolic reprogramming toward aerobic glycolysis and lactate fermentation supplies
cancer cells with intermediate metabolites, which are used as macromolecule precursors …
cancer cells with intermediate metabolites, which are used as macromolecule precursors …
[HTML][HTML] Regulation of tumor-associated macrophage (TAM) differentiation by NDRG2 expression in breast cancer cells
S Lee, A Lee, J Lim, JS Lim - BMB reports, 2022 - ncbi.nlm.nih.gov
Macrophages are a major cellular component of innate immunity and are mainly known to
have phagocytic activity. In the tumor microenvironment (TME), they can be differentiated …
have phagocytic activity. In the tumor microenvironment (TME), they can be differentiated …
[HTML][HTML] Knock-down of NDRG2 sensitizes cervical cancer Hela cells to cisplatin through suppressing Bcl-2 expression
Background NDRG2, a member of N-Myc downstream regulated gene family, plays some
roles in cellular stress, cell differentiation and tumor suppression. We have found that …
roles in cellular stress, cell differentiation and tumor suppression. We have found that …
[HTML][HTML] Ndrg2 promoter hypermethylation triggered by helicobacter pylori infection correlates with poor patients survival in human gastric carcinoma
ZQ Ling, MH Ge, XX Lu, J Han, YC Wu, X Liu, X Zhu… - Oncotarget, 2015 - ncbi.nlm.nih.gov
N-myc downstream regulated gene 2 (Ndrg2) is a candidate suppressor of cancer
metastasis. We found that Ndrg2 promoter was frequently hypermethylated in gastric cancer …
metastasis. We found that Ndrg2 promoter was frequently hypermethylated in gastric cancer …
The tumor suppressor NDRG2 cooperates with an mTORC1 inhibitor to suppress the Warburg effect in renal cell carcinoma
X Li, G Hou, Z Zhu, F Yan, F Wang, D Wei… - Investigational New …, 2020 - Springer
Renal cell carcinoma (RCC) is one of the most common malignancies worldwide, and
metabolic reprogramming has a profound effect on RCC tumorigenesis. mTORC1 inhibitors …
metabolic reprogramming has a profound effect on RCC tumorigenesis. mTORC1 inhibitors …