Effects of paternal overnutrition and interventions on future generations

MM Billah, S Khatiwada, MJ Morris… - International journal of …, 2022 - nature.com
In the last two decades, evidence from human and animal studies suggests that paternal
obesity around the time of conception can have adverse effects on offspring health through …

Metabolic memory: mechanisms and diseases

H Dong, Y Sun, L Nie, A Cui, P Zhao… - Signal transduction and …, 2024 - nature.com
Metabolic diseases and their complications impose health and economic burdens
worldwide. Evidence from past experimental studies and clinical trials suggests our body …

The effects of cadmium on the development of Drosophila and its transgenerational inheritance effects

Y Mu, X Hu, P Yang, L Sun, W Gu, M Zhang - Toxicology, 2021 - Elsevier
A new focus in toxicology research is the impact of parental exposure to environmental toxic
substances on the characteristics of offspring. In the present study, newly produced eggs of …

Transgenerational effects of bisphenol A on zebrafish reproductive tissues and sperm motility

MH Mostari, MM Rahaman, MA Akhter, MH Ali… - Reproductive …, 2022 - Elsevier
In a previous study, we demonstrated the next-generation effects and further
transgenerational adverse effects of bisphenol A (BPA) in zebrafish. The adverse effects on …

Inherited Metabolic Memory of High‐Fat Diet Impairs Testicular Fatty Acid Content and Sperm Parameters

L Crisóstomo, RA Videira, I Jarak… - Molecular Nutrition & …, 2022 - Wiley Online Library
Scope Exposure to a high‐fat diet (HFD) from early‐life is associated with a testicular
metabolic signature link to abnormal sperm parameters up to two generations after exposure …

Dietary trends and the decline in male reproductive health

J Whittaker - Hormones, 2023 - Springer
Over the twentieth century, male reproductive health has suffered a substantial decline, as
evidenced by decreases in sperm counts and testosterone levels and increases in …

Novel insights into circRNA saga coming from spermatozoa and epididymis of HFD mice

F Manfrevola, T Chioccarelli, VG Mele… - International Journal of …, 2023 - mdpi.com
Obesity is a pathophysiological disorder associated with adiposity accumulation, oxidative
stress, and chronic inflammation state that is progressively increasing in younger population …

A systematic scientometric review of paternal inheritance of acquired metabolic traits

L Crisóstomo, PF Oliveira, MG Alves - BMC biology, 2023 - Springer
Background The concept of the inheritance of acquired traits, a foundational principle of
Lamarck's evolutionary theory, has garnered renewed attention in recent years. Evidence for …

Molecular mechanisms regulating spermatogenesis in vertebrates: Environmental, metabolic, and epigenetic factor effects

B Guerra-Carvalho, DF Carrageta, L Crisóstomo… - Animal Reproduction …, 2022 - Elsevier
The renewal of the natural resources is one of the most concerning aspects of modern
farming. In animal production, there are many barriers breeders and researchers have to …

Testicular “inherited metabolic memory” of ancestral high-fat diet is associated with sperm sncRNA content

L Crisóstomo, M Bourgery, L Rato, JF Raposo… - Biomedicines, 2022 - mdpi.com
Excessive adiposity caused by high-fat diets (HFDs) is associated with testicular metabolic
and functional abnormalities up to grand-offspring, but the mechanisms of this epigenetic …