NAD and NADP, a pivotal class of cofactors, which function as essential electron donors or
acceptors in all biological organisms, drive considerable catabolic and anabolic reactions …

Oxidoreductases are ubiquitous enzymes that catalyze an extensive range of chemical
reactions with great specificity, efficiency, and selectivity. Most oxidoreductases are …

The NADPH‐dependent secondary alcohol dehydrogenase from Thermoanaerobacter
ethanolicus (TeSADH), displaying broad substrate specificity and low enantioselectivity, was …

Many platform chemicals such as 1, 2, 4-butanetriol (BTO) are still derived from
petrochemicals. BTO as a versatile compound with applications ranging from …

Here we report a new robust nicotinamide dinucleotide phosphate cofactor analog (carba‐
NADP+) and its acceptance by many enzymes in the class of oxidoreductases. Replacing …

Cyclohexanone monooxygenases (CHMO) consume molecular oxygen and NADPH to
catalyze the valuable oxidation of cyclic ketones. However, CHMO usage is restricted by …

Production of chemicals from lignocellulosic biomass has been proposed as a suitable
replacement to petrochemicals. However, one inherent challenge of biomass utilization is …

OleT from Jeotgalicoccus sp. ATCC 8456 catalyzes the decarboxylation of ω‐functionalized
fatty acids to the corresponding alkenols, which can themselves serve as starting material for …

Changing the cofactor specificity of an enzyme from nicotinamide adenine dinucleotide 2′-
phosphate (NADPH) to the more abundant NADH is a common strategy for increasing …

Compounds containing chiral C–N bonds play a vital role in the composition of biologically
active natural products and small pharmaceutical molecules. Therefore, the development of …