Nanotechnology in peripheral nerve repair and reconstruction

CR Carvalho, J Silva-Correia, JM Oliveira… - Advanced drug delivery …, 2019 - Elsevier
The recent progress in biomaterials science and development of tubular conduits (TCs) still
fails in solving the current challenges in the treatment of peripheral nerve injuries (PNIs), in …

[HTML][HTML] Implantable biomaterials for peripheral nerve regeneration–technology trends and translational tribulations

A Sanchez Rezza, Y Kulahci, VS Gorantla… - … in Bioengineering and …, 2022 - frontiersin.org
The use of autografted nerve in surgical repair of peripheral nerve injuries (PNI) is severely
limited due to donor site morbidity and restricted tissue availability. As an alternative …

Electrospinning Multilayered Scaffolds Loaded with Melatonin and Fe3O4 Magnetic Nanoparticles for Peripheral Nerve Regeneration

X Chen, X Ge, Y Qian, H Tang, J Song… - Advanced Functional …, 2020 - Wiley Online Library
Peripheral nerve injury is a common clinical problem bringing heavy burden to patients, due
to its high incidence and unsatisfactory treatment. Nerve guidance conduit (NGC) is a …

[HTML][HTML] Advancement of Electrospun Nerve Conduit for Peripheral Nerve Regeneration: A Systematic Review (2016–2021)

SY Lee, SY Thow, S Abdullah, MH Ng… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Peripheral nerve injury (PNI) is a worldwide problem which hugely affects the quality of
patients' life. Nerve conduits are now the alternative for treatment of PNI to mimic the gold …

[HTML][HTML] Translational bioengineering strategies for peripheral nerve regeneration: opportunities, challenges, and novel concepts

KA Sarhane, C Qiu, TGW Harris… - Neural Regeneration …, 2023 - journals.lww.com
Peripheral nerve injuries remain a challenging problem in need of better treatment
strategies. Despite best efforts at surgical reconstruction and postoperative rehabilitation …

Multichannel Conduits with Fascicular Complementation: Significance in Long Segmental Peripheral Nerve Injury

PA Ramesh, S Sethuraman… - … Biomaterials Science & …, 2024 - ACS Publications
Despite the advances in tissue engineering approaches, reconstruction of long segmental
peripheral nerve defects remains unsatisfactory. Although autologous grafts with proper …

[HTML][HTML] Metabolites of Moringa oleifera Activate Physio-Biochemical Pathways for an Accelerated Functional Recovery after Sciatic Nerve Crush Injury in Mice

M Imran, G Hussain, A Hameed, I Iftikhar, M Ibrahim… - Metabolites, 2022 - mdpi.com
In this study, the functional metabolites of Moringa oleifera (MO) were screened to evaluate
their possible role in accelerated functional retrieval after peripheral nerve injury (PNI). MO …

Foeniculum vulgare (Fennel) promotes functional recovery and ameliorates oxidative stress following a lesion to the sciatic nerve in mouse model

A Imran, L Xiao, W Ahmad, H Anwar… - Journal of food …, 2019 - Wiley Online Library
Peripheral nerve injury is one of the major health concerns of the present era which can lead
to the long‐lasting disability and even demise. Currently, no effective and side effect free …

Pharmacological effects of melatonin as neuroprotectant in rodent model: a review on the current biological evidence

HY Tan, KY Ng, RY Koh, SM Chye - Cellular and Molecular Neurobiology, 2020 - Springer
The progressive loss of structure and functions of neurons, including neuronal death, is one
of the main factors leading to poor quality of life. Promotion of functional recovery of neuron …

[HTML][HTML] Nerve Wrap for Local Delivery of FK506/Tacrolimus Accelerates Nerve Regeneration

B Xiao, F Feturi, AJA Su, Y Van der Merwe… - International Journal of …, 2024 - mdpi.com
Peripheral nerve injuries (PNIs) occur frequently and can lead to devastating and permanent
sensory and motor function disabilities. Systemic tacrolimus (FK506) administration has …