Multidimensional data are being abundantly produced by modern analytical instrumentation,
calling for new and powerful data-processing techniques. Research in the last two decades …

This review focuses on the applications and challenges of multi-way calibrations in
electrochemical analysis based on the growing literature in this field. Chemometrics has …

The validation of an analytical procedure must be certified through the determination of
parameters known as figures of merit. For first order data, the acuracy, precision, robustness …

Second-order calibration methods are gaining widespread acceptance among the analytical
community mainly because:(1) a wide range of analytical instrumentation is available that …

Chemometric techniques for calibration with three-way signals are sufficiently developed for
their use in routine analysis. The advantage of the second order property (the possibility of …

We discuss and evaluate the current state of second-order and higher-order multivariate
calibration methods devoted to the determination of compounds in non-multilinear data …

Abstract β-blockers are the first-line therapeutic agents for treating cardiovascular diseases
and also a class of prohibited substances in athletic competitions. In this work, a smart …

Multivariate Curve Resolution Alternating Least Squares (MCR-ALS) can analyze three-way
data under the assumption of a trilinear model using the trilinearity constraint. However, the …

Multivariate curve resolution by alternating least squares (MCR‐ALS) with the aim of
achieving the electrochemical second order advantage has been applied to potential‐time …

A simple analytical method based on the second-order calibration of the pH gradient
spectrophotometric data was developed for assay of carminic acid (CA) in human plasma …