[HTML][HTML] The roles of electronic health records for clinical trials in low-and middle-income countries: scoping review
Background: Clinical trials are a crucial element in advancing medical knowledge and
developing new treatments by establishing the evidence base for safety and therapeutic …
developing new treatments by establishing the evidence base for safety and therapeutic …
Defining key design elements of registry-based randomised controlled trials: a scoping review
Background Traditional randomised controlled trials remain the gold standard for improving
clinical care but they do have their limitations, including their associated high costs, high …
clinical care but they do have their limitations, including their associated high costs, high …
The reporting of studies conducted using observational routinely collected health data statement for pharmacoepidemiology (RECORD-PE)
SM Langan, SAJ Schmidt, K Wing, V Ehrenstein… - bmj, 2018 - bmj.com
In pharmacoepidemiology, routinely collected data from electronic health records (including
primary care databases, registries, and administrative healthcare claims) are a resource for …
primary care databases, registries, and administrative healthcare claims) are a resource for …
Effect of donor sex on recipient mortality in transfusion
Background Conflicting observational evidence exists regarding the association between
the sex of red-cell donors and mortality among transfusion recipients. Evidence to inform …
the sex of red-cell donors and mortality among transfusion recipients. Evidence to inform …
A digital health algorithm to guide antibiotic prescription in pediatric outpatient care: a cluster randomized controlled trial
Excessive antibiotic use and antimicrobial resistance are major global public health threats.
We developed ePOCT+, a digital clinical decision support algorithm in combination with C …
We developed ePOCT+, a digital clinical decision support algorithm in combination with C …
A pragmatic randomized feasibility trial of influenza vaccines
Background The relative vaccine effectiveness (rVE) of high-dose quadrivalent influenza
vaccines (QIV-HD) versus standard-dose quadrivalent influenza vaccines (QIV-SD) against …
vaccines (QIV-HD) versus standard-dose quadrivalent influenza vaccines (QIV-SD) against …
Designing and undertaking randomised implementation trials: guide for researchers
Implementation science is the study of methods to promote the systematic uptake of
evidence based interventions into practice and policy to improve health. Despite the need …
evidence based interventions into practice and policy to improve health. Despite the need …
Health characteristics and aspirin use in participants at the baseline of the aspirin in reducing events in the elderly–eXTension (ASPREE-XT) observational study
Background Aspirin as a primary preventative in healthy older adults did not prolong
disability-free survival in the ASPREE randomized trial. Observational studies following …
disability-free survival in the ASPREE randomized trial. Observational studies following …
Comparison of the accuracy and completeness of records of serious vascular events in routinely collected data vs clinical trial–adjudicated direct follow-up data in the …
C Harper, M Mafham, W Herrington, N Staplin… - JAMA Network …, 2021 - jamanetwork.com
Importance Routinely collected data could substantially decrease the cost of conducting
trials. Objective To assess the accuracy and completeness of UK routine data for …
trials. Objective To assess the accuracy and completeness of UK routine data for …
Scoping review and bibliometric analysis of Big Data applications for Medication adherence: an explorative methodological study to enhance consistency in literature
S Pirri, V Lorenzoni, G Turchetti - BMC Health Services Research, 2020 - Springer
Background Medication adherence has been studied in different settings, with different
approaches, and applying different methodologies. Nevertheless, our knowledge and …
approaches, and applying different methodologies. Nevertheless, our knowledge and …