Concerns about the widespread use of rodent models for human risk assessments of endocrine disruptors
R Habert, V Muczynski, T Grisin, D Moison… - …, 2014 - rep.bioscientifica.com
Fetal testis is a major target of endocrine disruptors (EDs). During the last 20 years, we have
developed an organotypic culture system that maintains the function of the different fetal …
developed an organotypic culture system that maintains the function of the different fetal …
Cholesterol and male fertility: what about orphans and adopted?
S Maqdasy, M Baptissart, A Vega, S Baron… - Molecular and cellular …, 2013 - Elsevier
The link between cholesterol homeostasis and male fertility has been clearly suggested in
patients who suffer from hyperlipidemia and metabolic syndrome. This has been confirmed …
patients who suffer from hyperlipidemia and metabolic syndrome. This has been confirmed …
[HTML][HTML] Dose-dependent ameliorative effects of quercetin and l-Carnitine against atrazine-induced reproductive toxicity in adult male Albino rats
This study aimed to determine the protective effects of co-administration of Quercetin (QT) or
l-Carnitine (LC) against the oxidative stress induced by Atrazine (ATZ) in the reproductive …
l-Carnitine (LC) against the oxidative stress induced by Atrazine (ATZ) in the reproductive …
[HTML][HTML] Autoantigens in ovarian autoimmunity associated with unexplained infertility and premature ovarian failure
SL Edassery, SV Shatavi, JP Kunkel, C Hauer… - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To identify ovarian autoantigens associated with ovarian autoantibodies.
DESIGN: Hypothesis-generating prospective study. SETTING: Urban infertility referral …
DESIGN: Hypothesis-generating prospective study. SETTING: Urban infertility referral …
Use of organ culture to study the human fetal testis development: effect of retinoic acid
R Lambrot, H Coffigny, C Pairault… - The Journal of …, 2006 - academic.oup.com
Context: In human, the chronology of the testicular development has been extensively
studied, but the factors implicated in the onset and the regulation of gametogenesis and …
studied, but the factors implicated in the onset and the regulation of gametogenesis and …
Retinoic acid prevents germ cell mitotic arrest in mouse fetal testes
E Trautmann, MJ Guerquin, C Duquenne, JB Lahaye… - Cell cycle, 2008 - Taylor & Francis
During mouse fetal development, meiosis is initiated in female germ cells only, with male
germ cells undergoing mitotic arrest. Retinoic acid (RA) is degraded by Cyp26b1 in the …
germ cells undergoing mitotic arrest. Retinoic acid (RA) is degraded by Cyp26b1 in the …
Organotypic culture, a powerful model for studying rat and mouse fetal testis development
G Livera, G Delbes, C Pairault, V Rouiller-Fabre… - Cell and tissue …, 2006 - Springer
The key role of the fetal testis in the masculinization of genital organs has been known for a
long time. More recently, the observed increases in male reproductive disorders has been …
long time. More recently, the observed increases in male reproductive disorders has been …
Adipose tissue-derived and bone marrow-derived mesenchymal cells develop into different lineage of steroidogenic cells by forced expression of steroidogenic factor …
S Gondo, T Okabe, T Tanaka, H Morinaga… - …, 2008 - academic.oup.com
Steroidogenic factor 1 (SF-1)/adrenal 4 binding protein is an essential nuclear receptor for
steroidogenesis, as well as for adrenal and gonadal gland development. We have …
steroidogenesis, as well as for adrenal and gonadal gland development. We have …
Nuclear receptors in Leydig cell gene expression and function
LJ Martin, JJ Tremblay - Biology of reproduction, 2010 - academic.oup.com
Several signals, such as hormones and signaling molecules, have been identified as
important regulators of Leydig cell differentiation and function. Conveying these signals and …
important regulators of Leydig cell differentiation and function. Conveying these signals and …
The retinoid X receptor agonist bexarotene relieves positive symptoms of schizophrenia: a 6-week, randomized, double-blind, placebo-controlled multicenter trial
V Lerner, C Miodownik, A Gibel, P Sirota… - The Journal of clinical …, 2013 - psychiatrist.com
The Retinoid X Receptor Agonist Bexarotene Relieves Positive Symptoms of Schizophrenia:
A 6-Week, Randomized, Double-Blind, Placebo-Controlled Multicenter Trial | Psychiatrist.com …
A 6-Week, Randomized, Double-Blind, Placebo-Controlled Multicenter Trial | Psychiatrist.com …