Diversity in NMDA receptor composition: many regulators, many consequences
A Sanz-Clemente, RA Nicoll… - The Neuroscientist, 2013 - journals.sagepub.com
N-methyl-D-aspartate receptors (NMDARs) are a subtype of ionotropic glutamate receptor,
which play a central role in learning, memory, and synaptic development. NMDARs are …
which play a central role in learning, memory, and synaptic development. NMDARs are …
Acute mechanisms underlying antibody effects in anti–N‐methyl‐D‐aspartate receptor encephalitis
Objective A severe but treatable form of immune‐mediated encephalitis is associated with
antibodies in serum and cerebrospinal fluid (CSF) against the GluN1 subunit of the N …
antibodies in serum and cerebrospinal fluid (CSF) against the GluN1 subunit of the N …
NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders
CG Lau, RS Zukin - Nature Reviews Neuroscience, 2007 - nature.com
The number and subunit composition of synaptic N-methyl-d-aspartate receptors (NMDARs)
are not static, but change in a cell-and synapse-specific manner during development and in …
are not static, but change in a cell-and synapse-specific manner during development and in …
[HTML][HTML] Human GRIN2B variants in neurodevelopmental disorders
The development of whole exome/genome sequencing technologies has given rise to an
unprecedented volume of data linking patient genomic variability to brain disorder …
unprecedented volume of data linking patient genomic variability to brain disorder …
Regulation of NMDA receptor subunit expression and its implications for LTD, LTP, and metaplasticity
K Yashiro, BD Philpot - Neuropharmacology, 2008 - Elsevier
NMDA-type glutamate receptors (NMDARs) mediate many forms of synaptic plasticity. These
tetrameric receptors consist of two obligatory NR1 subunits and two regulatory subunits …
tetrameric receptors consist of two obligatory NR1 subunits and two regulatory subunits …
GluN2A and GluN2B subunit-containing NMDA receptors in hippocampal plasticity
OA Shipton, O Paulsen - Philosophical Transactions of …, 2014 - royalsocietypublishing.org
N-Methyl-d-aspartate receptor (NMDAR)-dependent synaptic plasticity is a strong candidate
to mediate learning and memory processes that require the hippocampus. This plasticity is …
to mediate learning and memory processes that require the hippocampus. This plasticity is …
Regulation of NMDA glutamate receptor functions by the GluN2 subunits
The N‐methyl‐D‐aspartate receptors (NMDARs) are ionotropic glutamate receptors that
mediate the flux of calcium (Ca2+) into the post‐synaptic compartment. Ca2+ influx …
mediate the flux of calcium (Ca2+) into the post‐synaptic compartment. Ca2+ influx …
Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function
LA Raymond, VM André, C Cepeda, CM Gladding… - Neuroscience, 2011 - Elsevier
Huntington's disease (HD) is a progressive, fatal neurological condition caused by an
expansion of CAG (glutamine) repeats in the coding region of the Huntington gene. To date …
expansion of CAG (glutamine) repeats in the coding region of the Huntington gene. To date …
Regulation of NMDA receptors by phosphorylation
BS Chen, KW Roche - Neuropharmacology, 2007 - Elsevier
N-Methyl-d-aspartate (NMDA) receptors are critical for neuronal development and synaptic
plasticity. The molecular mechanisms underlying the synaptic localization and functional …
plasticity. The molecular mechanisms underlying the synaptic localization and functional …
Distinct modes of AMPA receptor suppression at developing synapses by GluN2A and GluN2B: single-cell NMDA receptor subunit deletion in vivo
During development there is an activity-dependent switch in synaptic N-Methyl-D-aspartate
(NMDA) receptor subunit composition from predominantly GluN2B to GluN2A, though the …
(NMDA) receptor subunit composition from predominantly GluN2B to GluN2A, though the …