Application of the all-hydrocarbon stapling technique in the design of membrane-active peptides
The threats of drug resistance and new emerging pathogens have led to an urgent need to
develop alternative treatment therapies. Recently, considerable research efforts have …
develop alternative treatment therapies. Recently, considerable research efforts have …
[HTML][HTML] Natural peptides inducing cancer cell death: Mechanisms and properties of specific candidates for cancer therapeutics
PA Trinidad-Calderón, CD Varela-Chinchilla… - Molecules, 2021 - mdpi.com
Nowadays, cancer has become the second highest leading cause of death, and it is
expected to continue to affect the population in forthcoming years. Additionally, treatment …
expected to continue to affect the population in forthcoming years. Additionally, treatment …
Multiple roles of ribosomal antimicrobial peptides in tackling global antimicrobial resistance
In the last century, conventional antibiotics have played a significant role in global
healthcare. Antibiotics support the body in controlling bacterial infection and simultaneously …
healthcare. Antibiotics support the body in controlling bacterial infection and simultaneously …
Effect of substituting glutamine with lysine on structural and biological properties of antimicrobial peptide Polybia-MP1
HBT Phuong, VA Tran, KN Ngoc, VN Huu, HN Thu… - Amino Acids, 2023 - Springer
The natural antimicrobial peptide Polybia-MP1 is a promising candidate for developing new
treatment therapy for infection and cancer. It showed broad-spectrum antimicrobial and …
treatment therapy for infection and cancer. It showed broad-spectrum antimicrobial and …
[HTML][HTML] Isolation and Optimization of a Broad-Spectrum Synthetic Antimicrobial Peptide, Ap920-WI, from Arthrobacter sp. H5 for the Biological Control of Plant …
L Zhao, MS Islam, P Song, L Zhu, W Dong - International Journal of …, 2023 - mdpi.com
Antimicrobial peptides (AMPs) are naturally occurring molecules found in various organisms
that can help to defend against invading microorganisms and reduce the likelihood of drug …
that can help to defend against invading microorganisms and reduce the likelihood of drug …
[HTML][HTML] Bioengineered bacterial outer membrane vesicles encapsulated Polybia–mastoparan I fusion peptide as a promising nanoplatform for bladder cancer …
Background Nanosized bacterial outer membrane vesicles (OMVs) secreted by Gram-
negative bacteria have emerged as a novel antitumor nanomedicine reagent due to their …
negative bacteria have emerged as a novel antitumor nanomedicine reagent due to their …
[HTML][HTML] Bioactive peptides and proteins from wasp venoms
L Luo, PM Kamau, R Lai - Biomolecules, 2022 - mdpi.com
Wasps, members of the order Hymenoptera, use their venom for predation and defense.
Accordingly, their venoms contain various constituents acting on the circulatory, immune and …
Accordingly, their venoms contain various constituents acting on the circulatory, immune and …
Impact of chemical modifications on the antimicrobial and hemolytic activity of helical amphipathic peptide Lasioglossin LL-III
H Bui Thi Phuong, C Le Uyen, H Doan Ngan… - Amino Acids, 2023 - Springer
Insect venom is abundant in potential antimicrobial peptides (AMPs), which can serve as
novel alternatives to conventional antibiotics. Among them, Lasioglossin III LL-III) is a …
novel alternatives to conventional antibiotics. Among them, Lasioglossin III LL-III) is a …
[HTML][HTML] Unwrapping the structural and functional features of antimicrobial peptides from wasp venoms
HM Duque, C Dos Santos, J Brango-Vanegas… - Pharmacological …, 2024 - Elsevier
The study of wasp venoms has captured attention due to the presence of a wide variety of
active compounds, revealing a diverse array of biological effects. Among these compounds …
active compounds, revealing a diverse array of biological effects. Among these compounds …
The amphipathic design in helical antimicrobial peptides
H Bui Thi Phuong, H Doan Ngan, B Le Huy… - …, 2024 - Wiley Online Library
Amphipathicity is a critical characteristic of helical antimicrobial peptides (AMPs). The
hydrophilic region, primarily composed of cationic residues, plays a pivotal role in the initial …
hydrophilic region, primarily composed of cationic residues, plays a pivotal role in the initial …