Possible role of LCZ696 in atherosclerosis: new inroads and perspective
LCZ696 blocks both angiotensin receptor type 1 (ATR1) and neprilysin (NEP), which are
intricate in the degradation of natriuretic peptides (NPs) and other endogenous peptides. It …
intricate in the degradation of natriuretic peptides (NPs) and other endogenous peptides. It …
Angiotensinogen as a Therapeutic Target for Cardiovascular and Metabolic Diseases
AGT (angiotensinogen) is the unique precursor for the generation of all the peptides of the
renin-angiotensin system, but it has received relatively scant attention compared to many …
renin-angiotensin system, but it has received relatively scant attention compared to many …
Effectiveness and Tolerability of Bisoprolol/Perindopril Single-Pill Combination in Patients with Arterial Hypertension and a History of Myocardial Infarction: The PRIDE …
Z Kobalava, B Kvasnikov, Y Burtsev… - Advances in …, 2023 - Springer
Introduction This study assessed the real-life effectiveness of a single-pill combination (SPC)
of bisoprolol/perindopril for controlling blood pressure (BP) and symptoms of angina in …
of bisoprolol/perindopril for controlling blood pressure (BP) and symptoms of angina in …
The pivotal role of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers in hypertension management and cardiovascular and renal …
LA Alcocer, A Bryce, D De Padua Brasil, J Lara… - American Journal of …, 2023 - Springer
Arterial hypertension is the main preventable cause of premature mortality worldwide.
Across Latin America, hypertension has an estimated prevalence of 25.5–52.5%, although …
Across Latin America, hypertension has an estimated prevalence of 25.5–52.5%, although …
ACEI and ARB—Each Unique RAAS Inhibitors: The Importance of Impact on Inflammation
MH Strauss, AS Hall… - Mayo Clinic …, 2023 - mayoclinicproceedings.org
To the Editor: In a meta-analysis of angiotensin-converting enzyme inhibitors (ACEi) and
angiotensin receptor blocker (ARB) randomized placebo controlled trials, Awad et al 1 …
angiotensin receptor blocker (ARB) randomized placebo controlled trials, Awad et al 1 …
ACE inhibitors and the risk of lung cancer—is there causality?
A current debate relates to the risk of cancer associated with some antihypertensive drugs
[1]. This includes both angiotensinconverting enzyme inhibitors (ACEI) and angiotensin II …
[1]. This includes both angiotensinconverting enzyme inhibitors (ACEI) and angiotensin II …
Characteristics, Treatment, and In-Hospital Outcomes of Older Patients With STEMI Without Standard Modifiable Risk Factors
G Zhao, M Zhou, X Zhao, C Ma, Y Han, J Liu, D Zhao… - JACC: Asia, 2024 - jacc.org
Background Strategies targeting standard modifiable cardiovascular risk factors (SMuRFs),
including hypertension, diabetes, hypercholesterolemia, and smoking, have been well …
including hypertension, diabetes, hypercholesterolemia, and smoking, have been well …
Roadmap for the Management of Type 2 Diabetes and Hypertension in the Middle East: Review of the 2022 EVIDENT Summit
Y Al Saleh, N Al Busaidi, W Al Dahi, M Almajnoni… - Advances in …, 2023 - Springer
Type 2 diabetes mellitus (T2DM) and hypertension are leading risk factors for death and
disability in the Middle East. Both conditions are highly prevalent, underdiagnosed and …
disability in the Middle East. Both conditions are highly prevalent, underdiagnosed and …
Chronic exercise improves renal AT1 and ETB receptor functions via modulating GRK4 expression in obese Zucker rats
J Lu, Z Li, Y Yang, F Wei - Clinical and Experimental Hypertension, 2024 - Taylor & Francis
Background Physical activity has profound benefits on health, especially in patients with
cardiovascular and metabolic disease. Exercise training can reduce oxidative stress …
cardiovascular and metabolic disease. Exercise training can reduce oxidative stress …
In Reply: Real-World Evidence for Causal Inference—Are We Ready?
S Oh, JH Kim, KH Cho, MC Kim… - Mayo Clinic …, 2023 - mayoclinicproceedings.org
2. Strauss MH, Hall AS. Angiotensin receptor blockers do not reduce risk of myocardial
infarction, cardiovascular death, or total mortality: further evidence for the ARB-MI paradox …
infarction, cardiovascular death, or total mortality: further evidence for the ARB-MI paradox …