The acid dissociation constant (pKa) is among the most frequently used physicochemical
parameters, and its determination is of interest to a wide range of research fields. We …

The pK a values of functional groups is crucial in determining the pharmacokinetic
properties of a drug, affecting its absorption and thus bioavailability. This physicochemical …

Using complementary approaches of potentiometry and NMR spectroscopy, we have
determined that the equilibrium acid dissociation constant (pKa value) of the arginine …

The p K a values and charge states of ionizable residues in polypeptides and proteins are
frequently determined via NMR-monitored pH titrations. To aid the interpretation of the …

The interaction between cyanidin-3-O-glucoside and four citrus pectic fractions was
investigated using a combined molecular approach, including isothermal titration calorimetry …

pH is an important parameter in condensed-phase systems, because it determines the
protonation state of titratable groups and thus influences the structure, dynamics, and …

Biofilms are often associated with human bacterial infections, and the natural tolerance of
biofilms to antibiotics challenges treatment. Compounds with antibiofilm activity could …

Antifungal drugs such as amphotericin B (AmB) interact with lipids and phospholipids
located on fungal cell membranes to disrupt them and create pores, leading to cell apoptosis …

The impact of grape pectic polysaccharides on malvidin-3-O-β-d-glucoside thermostability
was evaluated in model solutions. Pectic polysaccharides richer in homogalacturonan …

In this work Polyaniline and its doped state with microfiber morphologies were easily
synthesized by chemical route under the oxidative polymerization, in which the …