[HTML][HTML] Optimizing therapies using therapeutic drug monitoring: current strategies and future perspectives

PM Irving, KB Gecse - Gastroenterology, 2022 - Elsevier
Therapeutic drug monitoring (TDM) has emerged as a strategy for treatment optimization in
inflammatory bowel diseases to maximize benefit and to reach more stringent, objective end …

Recent advances in clinical practice: management of inflammatory bowel disease during the COVID-19 pandemic

S Lin, LHS Lau, N Chanchlani, NA Kennedy, SC Ng - Gut, 2022 - gut.bmj.com
The COVID-19 pandemic has raised considerable concerns that patients with inflammatory
bowel disease (IBD), particularly those treated with immunosuppressive therapies, may …

[HTML][HTML] Point-of-care testing and home testing: pragmatic considerations for widespread incorporation of stool tests, serum tests, and intestinal ultrasound

R Wilkens, M Dolinger, J Burisch, C Maaser - Gastroenterology, 2022 - Elsevier
Breaking through the biologic therapy efficacy plateau for inflammatory bowel disease
requires the strategic development of personalized biomarkers in the tight control model …

Recent advances in clearance monitoring of monoclonal antibodies in patients with inflammatory bowel diseases

W Kantasiripitak, Z Wang, I Spriet… - Expert Review of …, 2021 - Taylor & Francis
Introduction Less than 50% of patients with inflammatory bowel diseases (IBD) receiving
monoclonal antibody (mAb) therapy achieve endoscopic remission. Poor outcomes may …

Therapeutic drug monitoring 2.0: Time to assemble the puzzle

Z Wang, E Dreesen - Inflammatory Bowel Diseases, 2024 - academic.oup.com
Apart from the Norwegian Drug Monitoring study (NORDRUM) B study, prospective
therapeutic drug monitoring (TDM) studies have largely failed to show the benefit of TDM for …

Optimizing therapeutic drug monitoring in inflammatory bowel disease: a focus on therapeutic monoclonal antibodies

K Papamichael, AS Cheifetz - Expert Opinion on Drug Metabolism …, 2021 - Taylor & Francis
Introduction Therapeutic drug monitoring (TDM) is useful for optimizing monoclonal
antibodies (mAbs) for the treatment of immune-mediated inflammatory disorders including …

Clinical validation of a capillary blood home-based self-sampling technique for monitoring of infliximab, vedolizumab, and C-reactive protein concentrations in patients …

AT Otten, HH van der Meulen… - Inflammatory Bowel …, 2024 - academic.oup.com
Background Therapeutic drug monitoring provides important guidance for treatment of
patients with inflammatory bowel disease (IBD) and could help to early identify treatment …

[HTML][HTML] Utility and limitations of monitoring kidney transplants using capillary sampling

DJ Whitbread, R Nice, S Benyon… - Clinical Chemistry and …, 2024 - degruyter.com
Renal transplant patients require regular monitoring of graft function and Tacrolimus levels.
This is thrice-weekly post-operatively, and those 1 year post-transplant are reviewed 3–6 …

Cross-sectional evaluation of online direct-to-public calprotectin testing

M Bishara, R Smith, C Roberts, Y Djouider… - Frontline …, 2024 - fg.bmj.com
Objective Why about a quarter of patients with inflammatory bowel disease (IBD) suffer
symptoms for more than a year before their diagnosis made is unclear. Low public …

New tools for therapeutic drug monitoring: making big things out of small pieces

E Dreesen - Journal of Crohn's and Colitis, 2022 - academic.oup.com
'Science is about rejecting hypotheses, not confirming them.'Just like that, TAXIT, TAILORIX,
and NOR-DRUM cannot be considered evidence for a 'lack of benefit'of therapeutic drug …