Treatment with synthetic glucocorticoids and the hypothalamus-pituitary-adrenal axis
RM Paragliola, G Papi, A Pontecorvi… - International journal of …, 2017 - mdpi.com
Chronic glucocorticoid (GC) treatment represents a widely-prescribed therapy for several
diseases in consideration of both anti-inflammatory and immunosuppressive activity but, if …
diseases in consideration of both anti-inflammatory and immunosuppressive activity but, if …
[HTML][HTML] How to manage patients with corticosteroids in oncology in the era of immunotherapy?
M Aldea, E Orillard, L Mansi, A Marabelle… - European Journal of …, 2020 - Elsevier
Corticosteroids are among the most prescribed drugs in oncology. The indications range
from cancer-related indications for refractory symptoms, anti-cancer effects mainly in …
from cancer-related indications for refractory symptoms, anti-cancer effects mainly in …
Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance
Despite unprecedented responses of some cancers to immune checkpoint blockade (ICB)
therapies, the application of checkpoint inhibitors in pancreatic cancer has been …
therapies, the application of checkpoint inhibitors in pancreatic cancer has been …
[HTML][HTML] Exploration of radiation-induced lung injury, from mechanism to treatment: a narrative review
Y Yan, J Fu, RO Kowalchuk, CM Wright… - … lung cancer research, 2022 - ncbi.nlm.nih.gov
Methods PubMed was used to collect articles about RILI from 1995 to 2021. The papers
included clinical trials, reviews, as well as systematic reviews and meta-analyses. Based on …
included clinical trials, reviews, as well as systematic reviews and meta-analyses. Based on …
[HTML][HTML] Glucocorticoids improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels
Z Xiang, J Liu, D Shi, W Chen, J Li, R Yan… - … Journal of Biological …, 2020 - ncbi.nlm.nih.gov
COVID-19 is a public health emergency that has rapidly spread to over 200 countries and
regions, and no effective treatment has been established to date. Severe and critical cases …
regions, and no effective treatment has been established to date. Severe and critical cases …
Benefits of Cardamom (Elettaria cardamomum (L.) Maton) and Turmeric (Curcuma longa L.) Extracts for Their Applications as Natural Anti-Inflammatory Adjuvants
GR Cárdenas Garza, JH Elizondo Luévano… - Plants, 2021 - mdpi.com
The genus Zingiberaceae has been widely used for phytotherapeutic purposes in traditional
medicine throughout the world for its anti-inflammatory activity. Experimental studies have …
medicine throughout the world for its anti-inflammatory activity. Experimental studies have …
Glucocorticoids and cognitive function: a walkthrough in endogenous and exogenous alterations
D De Alcubierre, D Ferrari, G Mauro, AM Isidori… - Journal of …, 2023 - Springer
Purpose The hypothalamic–pituitary–adrenal (HPA) axis exerts many actions on the central
nervous system (CNS) aside from stress regulation. Glucocorticoids (GCs) play an important …
nervous system (CNS) aside from stress regulation. Glucocorticoids (GCs) play an important …
[HTML][HTML] Glucocorticoids are double-edged sword in the treatment of COVID-19 and cancers
R Yang, Y Yu - International journal of biological sciences, 2021 - ncbi.nlm.nih.gov
Glucocorticoids are important steroid hormones. As an outstanding scientific discovery, the
scientist who discovered glucocorticoids was awarded the Nobel Prize in Physiology and …
scientist who discovered glucocorticoids was awarded the Nobel Prize in Physiology and …
The pathophysiology of farnesoid X receptor (FXR) in the GI tract: inflammation, barrier function and innate immunity
KM Anderson, CP Gayer - Cells, 2021 - mdpi.com
The Farnesoid-X Receptor, FXR, is a nuclear bile acid receptor. Its originally described
function is in bile acid synthesis and regulation within the liver. More recently, however, FXR …
function is in bile acid synthesis and regulation within the liver. More recently, however, FXR …
Inhaled corticosteroids in adults with non-cystic fibrosis bronchiectasis: from bench to bedside. A narrative review
MÁ Martínez-García, G Oscullo, A García-Ortega… - Drugs, 2022 - Springer
Due to their potent anti-inflammatory capacity (particularly in predominantly eosinophilic
inflammation) and immunosuppressive properties, inhaled corticosteroids (ICSs) are widely …
inflammation) and immunosuppressive properties, inhaled corticosteroids (ICSs) are widely …