Chromatin accessibility profiling by ATAC-seq
The assay for transposase-accessible chromatin using sequencing (ATAC-seq) provides a
simple and scalable way to detect the unique chromatin landscape associated with a cell …
simple and scalable way to detect the unique chromatin landscape associated with a cell …
Joint profiling of histone modifications and transcriptome in single cells from mouse brain
Genome-wide profiling of histone modifications can reveal not only the location and activity
state of regulatory elements, but also the regulatory mechanisms involved in cell-type …
state of regulatory elements, but also the regulatory mechanisms involved in cell-type …
Simultaneous trimodal single-cell measurement of transcripts, epitopes, and chromatin accessibility using TEA-seq
E Swanson, C Lord, J Reading, AT Heubeck… - Elife, 2021 - elifesciences.org
Single-cell measurements of cellular characteristics have been instrumental in
understanding the heterogeneous pathways that drive differentiation, cellular responses to …
understanding the heterogeneous pathways that drive differentiation, cellular responses to …
An ultra high-throughput method for single-cell joint analysis of open chromatin and transcriptome
Simultaneous profiling of transcriptome and chromatin accessibility within single cells is a
powerful approach to dissect gene regulatory programs in complex tissues. However …
powerful approach to dissect gene regulatory programs in complex tissues. However …
Hydrop enables droplet-based single-cell ATAC-seq and single-cell RNA-seq using dissolvable hydrogel beads
FV De Rop, JN Ismail, CB González-Blas… - Elife, 2022 - elifesciences.org
Single-cell RNA-seq and single-cell assay for transposase-accessible chromatin (ATAC-
seq) technologies are used extensively to create cell type atlases for a wide range of …
seq) technologies are used extensively to create cell type atlases for a wide range of …
Genome-wide ATAC-see screening identifies TFDP1 as a modulator of global chromatin accessibility
S Ishii, T Kakizuka, SJ Park, A Tagawa, C Sanbo… - Nature …, 2024 - nature.com
Chromatin accessibility is a hallmark of active regulatory regions and is functionally linked to
transcriptional networks and cell identity. However, the molecular mechanisms and networks …
transcriptional networks and cell identity. However, the molecular mechanisms and networks …
Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in zebrafish embryos
AC McGarvey, W Kopp, D Vučićević, K Mattonet… - Cell Genomics, 2022 - cell.com
DNA accessibility of cis-regulatory elements (CREs) dictates transcriptional activity and
drives cell differentiation during development. While many genes regulating embryonic …
drives cell differentiation during development. While many genes regulating embryonic …
Chromatin profiling techniques: exploring the chromatin environment and its contributions to complex traits
The genetic architecture of complex traits is multifactorial. Genome-wide association studies
(GWASs) have identified risk loci for complex traits and diseases that are disproportionately …
(GWASs) have identified risk loci for complex traits and diseases that are disproportionately …
High-capacity sample multiplexing for single cell chromatin accessibility profiling
Single-cell chromatin accessibility has emerged as a powerful means of understanding the
epigenetic landscape of diverse tissues and cell types, but profiling cells from many …
epigenetic landscape of diverse tissues and cell types, but profiling cells from many …
TEA-seq: a trimodal assay for integrated single cell measurement of transcription, epitopes, and chromatin accessibility
E Swanson, C Lord, J Reading, AT Heubeck… - bioRxiv, 2020 - biorxiv.org
Single-cell measurements of cellular characteristics have been instrumental in
understanding the heterogeneous pathways that drive differentiation, cellular responses to …
understanding the heterogeneous pathways that drive differentiation, cellular responses to …