Resveratrol (RV) is a well-known polyphenolic compound in various plants, including grape,
peanut, and berry fruits, which is quite famous for its association with several health benefits …

Mitochondrial dysfunction constitutes one of the hallmarks of aging and is characterized by
irregular mitochondrial morphology, insufficient ATP production, accumulation of …

Parkinson's disease (PD) usually presents in older adults and typically has both motor and
non-motor dysfunctions. PD is a progressive neurodegenerative disorder resulting from …

Gradual degeneration and loss of dopaminergic neurons in the substantia nigra, pars
compacta and subsequent reduction of dopamine levels in striatum are associated with …

New discoveries providing insights into mitochondrial bioenergetics, their dynamic
interactions as well as their role in cellular homeostasis have dramatically advanced our …

Autophagy is a major, conserved cellular pathway by which cells deliver cytoplasmic
contents to lysosomes for degradation. Genetic studies have revealed extensive links …

Sirtuins are NAD+ dependent histone deacetylases (HDAC) that play a pivotal role in
neuroprotection and cellular senescence. SIRT1-7 are different homologs from sirtuins. They …

Converging evidence from genetic, pathological and experimental studies have increasingly
suggested an important role for autophagy impairment in Parkinson's Disease (PD). Genetic …

Alzheimer's disease (AD) is a progressive cortex and hippocampal neurodegenerative
disease which ultimately causes cognitively impaired decline in patients. The AD pathogen …

Resveratrol, a phytoalexin with a wide range of pharmacological properties is synthesised
by plants in response to stress, injury, infection or UV radiations. As it is a secondary …