Layered double hydroxide-based nanomaterials for biomedical applications

T Hu, Z Gu, GR Williams, M Strimaite, J Zha… - Chemical Society …, 2022 - pubs.rsc.org
Against the backdrop of increased public health awareness, inorganic nanomaterials have
been widely explored as promising nanoagents for various kinds of biomedical applications …

2D nanomaterials for cancer theranostic applications

L Cheng, X Wang, F Gong, T Liu, Z Liu - Advanced Materials, 2020 - Wiley Online Library
Abstract 2D nanomaterials with unique nanosheet structures, large surface areas, and
extraordinary physicochemical properties have attracted tremendous interest. In the area of …

Degradability and clearance of inorganic nanoparticles for biomedical applications

G Yang, SZF Phua, AK Bindra, Y Zhao - Advanced Materials, 2019 - Wiley Online Library
Inorganic nanoparticles with tunable and diverse properties hold tremendous potential in the
field of nanomedicine, while having non‐negligible toxicity concerns in healthy …

Extracellular vesicles and particles impact the systemic landscape of cancer

S Lucotti, CM Kenific, H Zhang, D Lyden - The EMBO journal, 2022 - embopress.org
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

Efficient immunotherapy of drug-free layered double hydroxide nanoparticles via neutralizing excess acid and blocking tumor cell autophagy

L Zhang, Y Jia, J Yang, L Zhang, S Hou, X Niu, J Zhu… - ACS …, 2022 - ACS Publications
Cancer immunotherapy efficacy is largely limited by the suppressive tumor immune
microenvironment (TIME) where antitumor immune cells are inhibited and tumor antigens …

Exosome-based tumor antigens–adjuvant co-delivery utilizing genetically engineered tumor cell-derived exosomes with immunostimulatory CpG DNA

M Morishita, Y Takahashi, A Matsumoto, M Nishikawa… - Biomaterials, 2016 - Elsevier
For cancer immunotherapy via tumor antigen vaccination in combination with an adjuvant,
major challenges include the identification of a particular tumor antigen and efficient delivery …

Lymph node targeting strategies to improve vaccination efficacy

H Jiang, Q Wang, X Sun - Journal of Controlled Release, 2017 - Elsevier
With the rapid development of nanotechnology as well as growing interest in
immunotherapy, a great number of vaccine delivery vehicles have been explored in order to …

Hierarchical layered double hydroxide nanocomposites: structure, synthesis and applications

Z Gu, JJ Atherton, ZP Xu - Chemical communications, 2015 - pubs.rsc.org
Layered double hydroxide (LDH)-based nanocomposites, constructed by interacting LDH
nanoparticles with other nanomaterials (eg silica nanoparticles and magnetic nanoparticles) …

Manganese‐Based Layered Double Hydroxide Nanoparticles as a T1‐MRI Contrast Agent with Ultrasensitive pH Response and High Relaxivity

B Li, Z Gu, N Kurniawan, W Chen, ZP Xu - Advanced Materials, 2017 - Wiley Online Library
Recently, Mn (II)‐containing nanoparticles have been explored widely as an attractive
alternative to Gd (III)‐based T1‐weighted magnetic resonance imaging (MRI) contrast …

Layered double hydroxide nanostructures and nanocomposites for biomedical applications

L Yan, S Gonca, G Zhu, W Zhang… - Journal of Materials …, 2019 - pubs.rsc.org
Layered double hydroxide (LDH) nanostructures and related nanocomposites have
attracted significant interest in biomedical applications including cancer therapy, bioimaging …