Hydroxytyrosol, tyrosol and derivatives and their potential effects on human health

A Karković Marković, J Torić, M Barbarić… - Molecules, 2019 - mdpi.com
The Mediterranean diet and olive oil as its quintessential part are almost synonymous with a
healthy way of eating and living nowadays. This kind of diet has been highly appreciated …

Amyloid beta: structure, biology and structure-based therapeutic development

G Chen, T Xu, Y Yan, Y Zhou, Y Jiang… - Acta Pharmacologica …, 2017 - nature.com
Amyloid beta peptide (Aβ) is produced through the proteolytic processing of a
transmembrane protein, amyloid precursor protein (APP), by β-and γ-secretases. Aβ …

Beneficial effects of the olive oil phenolic components oleuropein and hydroxytyrosol: focus on protection against cardiovascular and metabolic diseases

S Bulotta, M Celano, SM Lepore, T Montalcini… - Journal of translational …, 2014 - Springer
The overall health beneficial action of olive oil phenolic components is well established.
Recent studies have elucidated the biological effects of two isolated compounds, namely …

Oleuropein, a Bioactive Compound from Olea europaea L., as a Potential Preventive and Therapeutic Agent in Non-Communicable Diseases

C Nediani, J Ruzzolini, A Romani, L Calorini - Antioxidants, 2019 - mdpi.com
Growing scientific literature data suggest that the intake of natural bioactive compounds
plays a critical role in preventing or reducing the occurrence of human chronic non …

Nutraceutical properties of olive oil polyphenols. An itinerary from cultured cells through animal models to humans

S Rigacci, M Stefani - International journal of molecular sciences, 2016 - mdpi.com
The increasing interest in the Mediterranean diet hinges on its healthy and anti-ageing
properties. The composition of fatty acids, vitamins and polyphenols in olive oil, a key …

Effects of the olive-derived polyphenol oleuropein on human health

B Barbaro, G Toietta, R Maggio, M Arciello… - International journal of …, 2014 - mdpi.com
The use of the products derived from the olive tree on human health dates back centuries. In
several civilizations, the olive tree had and still has a very strong cultural and religious …

Oleuropein in olive and its pharmacological effects

SH Omar - Scientia pharmaceutica, 2010 - mdpi.com
Olive from Olea europaea is native to the Mediterranean region and, both the oil and the fruit
are some of the main components of the Mediterranean diet. The main active constituents of …

Alvespimycin exhibits potential anti-TGF-β signaling in the setting of a proteasome activator in rats with bleomycin-induced pulmonary fibrosis: a promising novel …

OA Mohammed, MA Abdel-Reheim, LA Saleh… - Pharmaceuticals, 2023 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is an irreversible and life-threatening lung disease of
unknown etiology presenting only a few treatment options. TGF-β signaling orchestrates a …

[HTML][HTML] Natural and synthetic antioxidants targeting cardiac oxidative stress and redox signaling in cardiometabolic diseases

M Barteková, A Adameová, A Görbe… - Free Radical Biology …, 2021 - Elsevier
Cardiometabolic diseases (CMDs) are metabolic diseases (eg, obesity, diabetes,
atherosclerosis, rare genetic metabolic diseases, etc.) associated with cardiac pathologies …

Olive by-products: Challenge application in cosmetic industry

F Rodrigues, FB Pimentel, MBPP Oliveira - Industrial Crops and Products, 2015 - Elsevier
Olive tree is a traditional plant which fruits (Olea europaea L.) are used for olive oil
production, especially in Mediterranean countries. Olive oil extraction produces by-products …