cis-Antisense RNA, Another Level of Gene Regulation in Bacteria

J Georg, WR Hess - Microbiology and Molecular Biology Reviews, 2011 - Am Soc Microbiol
SUMMARY A substantial amount of antisense transcription is a hallmark of gene expression
in eukaryotes. However, antisense transcription was first demonstrated in bacteria almost 50 …

Mitigating off‐target effects of small RNAs: conventional approaches, network theory and artificial intelligence

Z Bereczki, B Benczik, OM Balogh… - British Journal of …, 2025 - Wiley Online Library
Three types of highly promising small RNA therapeutics, namely, small interfering RNAs
(siRNAs), microRNAs (miRNAs) and the RNA subtype of antisense oligonucleotides (ASOs) …

IntaRNA 2.0: enhanced and customizable prediction of RNA–RNA interactions

M Mann, PR Wright, R Backofen - Nucleic acids research, 2017 - academic.oup.com
The IntaRNA algorithm enables fast and accurate prediction of RNA–RNA hybrids by
incorporating seed constraints and interaction site accessibility. Here, we introduce …

Long non-coding RNA NR2F1-AS1 induces breast cancer lung metastatic dormancy by regulating NR2F1 and ΔNp63

Y Liu, P Zhang, Q Wu, H Fang, Y Wang, Y Xiao… - Nature …, 2021 - nature.com
Disseminated tumor cells often fall into a long term of dormant stage, characterized by
decreased proliferation but sustained survival, in distant organs before awakening for …

The structure of the influenza A virus genome

B Dadonaite, B Gilbertson, ML Knight, S Trifkovic… - Nature …, 2019 - nature.com
Influenza A viruses (IAVs) constitute a major threat to human health. The IAV genome
consists of eight single-stranded viral RNA segments contained in separate viral …

An atlas of Hfq‐bound transcripts reveals 3′ UTRs as a genomic reservoir of regulatory small RNAs

Y Chao, K Papenfort, R Reinhardt, CM Sharma… - The EMBO …, 2012 - embopress.org
The small RNAs associated with the protein Hfq constitute one of the largest classes of post‐
transcriptional regulators known to date. Most previously investigated members of this class …

CopraRNA and IntaRNA: predicting small RNA targets, networks and interaction domains

PR Wright, J Georg, M Mann, DA Sorescu… - Nucleic acids …, 2014 - academic.oup.com
CopraRNA (Comparative prediction algorithm for small RNA targets) is the most recent asset
to the Freiburg RNA Tools webserver. It incorporates and extends the functionality of the …

SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization

ND Damas, M Marcatti, C Côme, LL Christensen… - Nature …, 2016 - nature.com
We currently have limited knowledge of the involvement of long non-coding RNAs
(lncRNAs) in normal cellular processes and pathologies. Here, we identify and characterize …

Small RNA interactome of pathogenic E. coli revealed through crosslinking of RNase E

SA Waters, SP McAteer, G Kudla, I Pang… - The EMBO …, 2017 - embopress.org
RNA sequencing studies have identified hundreds of non‐coding RNA s in bacteria,
including regulatory small RNA (sRNA). However, our understanding of sRNA function has …

Comparative genomics boosts target prediction for bacterial small RNAs

PR Wright, AS Richter, K Papenfort… - Proceedings of the …, 2013 - National Acad Sciences
Small RNAs (sRNAs) constitute a large and heterogeneous class of bacterial gene
expression regulators. Much like eukaryotic microRNAs, these sRNAs typically target …