cis-Antisense RNA, Another Level of Gene Regulation in Bacteria
SUMMARY A substantial amount of antisense transcription is a hallmark of gene expression
in eukaryotes. However, antisense transcription was first demonstrated in bacteria almost 50 …
in eukaryotes. However, antisense transcription was first demonstrated in bacteria almost 50 …
Mitigating off‐target effects of small RNAs: conventional approaches, network theory and artificial intelligence
Three types of highly promising small RNA therapeutics, namely, small interfering RNAs
(siRNAs), microRNAs (miRNAs) and the RNA subtype of antisense oligonucleotides (ASOs) …
(siRNAs), microRNAs (miRNAs) and the RNA subtype of antisense oligonucleotides (ASOs) …
IntaRNA 2.0: enhanced and customizable prediction of RNA–RNA interactions
The IntaRNA algorithm enables fast and accurate prediction of RNA–RNA hybrids by
incorporating seed constraints and interaction site accessibility. Here, we introduce …
incorporating seed constraints and interaction site accessibility. Here, we introduce …
Long non-coding RNA NR2F1-AS1 induces breast cancer lung metastatic dormancy by regulating NR2F1 and ΔNp63
Y Liu, P Zhang, Q Wu, H Fang, Y Wang, Y Xiao… - Nature …, 2021 - nature.com
Disseminated tumor cells often fall into a long term of dormant stage, characterized by
decreased proliferation but sustained survival, in distant organs before awakening for …
decreased proliferation but sustained survival, in distant organs before awakening for …
The structure of the influenza A virus genome
Influenza A viruses (IAVs) constitute a major threat to human health. The IAV genome
consists of eight single-stranded viral RNA segments contained in separate viral …
consists of eight single-stranded viral RNA segments contained in separate viral …
An atlas of Hfq‐bound transcripts reveals 3′ UTRs as a genomic reservoir of regulatory small RNAs
The small RNAs associated with the protein Hfq constitute one of the largest classes of post‐
transcriptional regulators known to date. Most previously investigated members of this class …
transcriptional regulators known to date. Most previously investigated members of this class …
CopraRNA and IntaRNA: predicting small RNA targets, networks and interaction domains
CopraRNA (Comparative prediction algorithm for small RNA targets) is the most recent asset
to the Freiburg RNA Tools webserver. It incorporates and extends the functionality of the …
to the Freiburg RNA Tools webserver. It incorporates and extends the functionality of the …
SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization
ND Damas, M Marcatti, C Côme, LL Christensen… - Nature …, 2016 - nature.com
We currently have limited knowledge of the involvement of long non-coding RNAs
(lncRNAs) in normal cellular processes and pathologies. Here, we identify and characterize …
(lncRNAs) in normal cellular processes and pathologies. Here, we identify and characterize …
Small RNA interactome of pathogenic E. coli revealed through crosslinking of RNase E
RNA sequencing studies have identified hundreds of non‐coding RNA s in bacteria,
including regulatory small RNA (sRNA). However, our understanding of sRNA function has …
including regulatory small RNA (sRNA). However, our understanding of sRNA function has …
Comparative genomics boosts target prediction for bacterial small RNAs
Small RNAs (sRNAs) constitute a large and heterogeneous class of bacterial gene
expression regulators. Much like eukaryotic microRNAs, these sRNAs typically target …
expression regulators. Much like eukaryotic microRNAs, these sRNAs typically target …