Purpose: The summary presented herein covers recommendations on the early detection of
prostate cancer and provides a framework to facilitate clinical decision-making in the …

The visualization of whole organs and organisms through tissue clearing and fluorescence
volumetric imaging has revolutionized the way we look at biological samples. Its application …

Background Screening for prostate cancer is burdened by a high rate of overdiagnosis. The
most appropriate algorithm for population-based screening is unknown. Methods We invited …

Background High rates of overdiagnosis are a critical barrier to organized prostate cancer
screening. Magnetic resonance imaging (MRI) with targeted biopsy has shown the potential …

Background and objective The transrectal biopsy approach is traditionally used to detect
prostate cancer. An alternative transperineal approach is historically performed under …

Background Systematic prostate biopsies add to the cancer detection rate of targeted
biopsies, but the explanation for that increased sensitivity is not yet clear. Objective To …

Cancers heavily threaten human life; therefore, a high‐accuracy diagnosis is vital to protect
human beings from the suffering of cancers. While biopsies and imaging methods are widely …

Context Although magnetic resonance imaging (MRI) is broadly implemented into active
surveillance (AS) protocols, data on the reliability of serial MRI in order to help guide follow …

Context Overdiagnosis as the argument to stop prostate cancer (PCa) screening is less valid
since the introduction of new technologies such as risk calculators (RCs) and magnetic …

Purpose: Transrectal prostate biopsy has come under scrutiny due to potential for post-
biopsy infections and transperineal prostate biopsy is being offered as the safer alternative …