Small molecule fluorescent probes for the detection of reactive nitrogen species in biological systems

Y Zhou, X Yang, S Xu, J Li, W Wang, M Yan - Coordination Chemistry …, 2023 - Elsevier
Reactive nitrogen species (RNS) as a class of vital reactive molecules, are essential for
maintaining homeostasis. Among RNS, nitric oxide (NO or NO.), peroxynitrite anion (ONOO …

Reaction-based fluorescent probes for the imaging of nitroxyl (HNO) in biological systems

B Dong, X Kong, W Lin - ACS Chemical Biology, 2017 - ACS Publications
Nitroxyl (HNO) has been identified as an important signaling molecule in biological systems
and plays critical roles in many physiological processes. Fluorescence imaging could …

Reaction-based off–on near-infrared fluorescent probe for imaging alkaline phosphatase activity in living cells and mice

Y Tan, L Zhang, KH Man, R Peltier… - … Applied Materials & …, 2017 - ACS Publications
Alkaline phosphatases are a group of enzymes that play important roles in regulating
diverse cellular functions and disease pathogenesis. Hence, developing fluorescent probes …

Iodinated xanthene-cyanine NIR dyes as potential photosensitizers for antimicrobial photodynamic therapy

TM Ebaston, F Nakonechny, E Talalai, G Gellerman… - Dyes and …, 2021 - Elsevier
Photosensitizers (PSs) are chemical entities that upon light exposure are able to produce
cytotoxic species such as singlet oxygen superoxide and free radicals. PSs are used in …

Imaging of anti-inflammatory effects of HNO via a near-infrared fluorescent probe in cells and in rat gouty arthritis model

Y Huang, X Zhang, N He, Y Wang, Q Kang… - Journal of Materials …, 2019 - pubs.rsc.org
Nitroxyl (HNO) plays a crucial role in anti-inflammatory effects via the inhibition of
inflammatory pathways, but the details of the endogenous generation of HNO still remain …

A novel dual-channel fluorescent probe for nitroxyl detection and its application in HepG-2 cells

Z Li, J Li, D Zhang, X Zhu, Y Ye, Y Zhao - Sensors and Actuators B …, 2020 - Elsevier
Intracellular nitroxyl (HNO) acts as an essential intermolecular signal to regulate a wide
variety of physiological and pathological processes. Nondestructive detection of HNO in …

A bioorthogonal 'turn-on'fluorescent probe for tracking mitochondrial nitroxyl formation

K Sunwoo, KN Bobba, JY Lim, T Park… - Chemical …, 2017 - pubs.rsc.org
A bioreductant-resistant 'turn-on'chemodosimetric fluorescent probe Mito-1 has been
developed for the detection of mitochondrial HNO in live cells. Mito-1 enables the detection …

ESIPT Active Assemblies for 'On‐On'Detection, Cell Imaging and Hampering Cellular Activity of 2, 6‐Dichloro‐4‐nitroaniline

M Devi, P Sharma, A Kumar, S Kaur… - Chemistry–An Asian …, 2022 - Wiley Online Library
ESIPT active PBI‐keto/enol assemblies have been developed which show 'on‐on'optical
response towards 2, 6‐dichloro‐4‐nitroaniline (DCN) due to a combined ESIPT‐AIEE …

Fluorescent probes for the detection of nitroxyl (HNO)

R Smulik-Izydorczyk, K Dębowska, J Pięta… - Free Radical Biology …, 2018 - Elsevier
Nitroxyl (HNO), which according to the IUPAC recommended nomenclature should be
named azanone, is the protonated one-electron reduction product of nitric oxide. Recently, it …

Imaging in the repair of peripheral nerve injury

ID Luzhansky, LC Sudlow, DM Brogan, MD Wood… - …, 2019 - Taylor & Francis
Surgical intervention followed by physical therapy remains the major way to repair damaged
nerves and restore function. Imaging constitutes promising, yet underutilized, approaches to …