The glycocalyx is a complex polysaccharide-protein layer lining the lumen of vascular
endothelial cells. Changes in the structure and function of the glycocalyx promote an …

Background Severe dengue often leads to poor clinical outcomes and high mortality; as a
result, it is of vital importance to find prognostic factors associated with the severe form of …

Abstract Background At present, the Americas report the largest number of cases of COVID-
19 worldwide. In this region, Mexico is the third country with most deaths (20,781 total …

Background Obesity is associated with unfavorable outcomes for infectious diseases. Most
researches exploring the association between nutritional status and dengue severity have …

Dengue-associated complications, including dengue shock syndrome, severe respiratory
distress, and pediatric acute liver failure (PALF), are associated with high mortality rates in …

Dengue fever is considered the most prolific vector-borne disease in the world, with its
transmission rate increasing more than eight times in the last two decades. While most …

The integrity of the endothelial glycocalyx (eGCX), a mixture of carbohydrates attached to
proteins expressed on the surface of blood vessel endothelial cells (EC), is critical for the …

Endothelial dysfunction leading to vascular permeability and plasma leakage are
characteristic features of severe dengue and sepsis. However, the mechanisms underlying …

T-cell–redirecting therapies are promising new therapeutic options in the field of cancer
immunotherapy, but the development of these modalities is challenging. A commonly …

Background: Dengue is a disease of major global importance. While most symptomatic
infections are mild, a small proportion of patients progress to severe disease with risk of …