Addiction is driven by excessive goal-directed drug choice under negative affect: translational critique of habit and compulsion theory
L Hogarth - Neuropsychopharmacology, 2020 - nature.com
Drug addiction may be a goal-directed choice driven by excessive drug value in negative
affective states, a habit driven by strong stimulus− response associations, or a compulsion …
affective states, a habit driven by strong stimulus− response associations, or a compulsion …
Sex differences in opioid and psychostimulant craving and relapse: a critical review
A widely held dogma in the preclinical addiction field is that females are more vulnerable
than males to drug craving and relapse. Here, we first review clinical studies on sex …
than males to drug craving and relapse. Here, we first review clinical studies on sex …
Sex differences in animal models: focus on addiction
The purpose of this review is to discuss ways to think about and study sex differences in
preclinical animal models. We use the framework of addiction, in which animal models have …
preclinical animal models. We use the framework of addiction, in which animal models have …
Toll-like receptors in the vascular system: sensing the dangers within
S Goulopoulou, CG McCarthy, RC Webb - Pharmacological reviews, 2016 - ASPET
Toll-like receptors (TLRs) are components of the innate immune system that respond to
exogenous infectious ligands (pathogen-associated molecular patterns, PAMPs) and …
exogenous infectious ligands (pathogen-associated molecular patterns, PAMPs) and …
Sex differences in the neurobiology of drug addiction
SAM Bobzean, AK DeNobrega, LI Perrotti - Experimental neurology, 2014 - Elsevier
Epidemiological data demonstrate that while women report lower rates of drug use than
men, the number of current drug users and abusers who are women continues to increase …
men, the number of current drug users and abusers who are women continues to increase …
Sex differences in the neural mechanisms mediating addiction: a new synthesis and hypothesis
In this review we propose that there are sex differences in how men and women enter onto
the path that can lead to addiction. Males are more likely than females to engage in risky …
the path that can lead to addiction. Males are more likely than females to engage in risky …
Corticotropin releasing factor: a key role in the neurobiology of addiction
Drug addiction is a chronically relapsing disorder characterized by loss of control over intake
and dysregulation of stress-related brain emotional systems. Since the discovery by Wylie …
and dysregulation of stress-related brain emotional systems. Since the discovery by Wylie …
Sex differences and the role of estradiol in mesolimbic reward circuits and vulnerability to cocaine and opiate addiction
SS Kokane, LI Perrotti - Frontiers in behavioral neuroscience, 2020 - frontiersin.org
Although both men and women become addicted to drugs of abuse, women transition to
addiction faster, experience greater difficulties remaining abstinent, and relapse more often …
addiction faster, experience greater difficulties remaining abstinent, and relapse more often …
Emergence of sex differences in the development of substance use and abuse during adolescence
C Kuhn - Pharmacology & therapeutics, 2015 - Elsevier
Substance use and abuse begin during adolescence. Male and female adolescent humans
initiate use at comparable rates, but males increase use faster. In adulthood, more men than …
initiate use at comparable rates, but males increase use faster. In adulthood, more men than …
Stress is a principal factor that promotes tobacco use in females
OV Torres, LE O'Dell - Progress in Neuro-Psychopharmacology and …, 2016 - Elsevier
Tobacco use is a major economic and health problem. It is particularly concerning that
women consume more tobacco products, have a more difficult time quitting smoking, and …
women consume more tobacco products, have a more difficult time quitting smoking, and …