Adhesion GPCRs as a putative class of metabotropic mechanosensors
N Scholz, KR Monk, RJ Kittel, T Langenhan - Adhesion G protein-coupled …, 2016 - Springer
Graphical Abstract Adhesion GPCRs as mechanosensors. Different aGPCR homologs and
their cognate ligands have been described in settings, which suggest that they function in a …
their cognate ligands have been described in settings, which suggest that they function in a …
Understanding the structural basis of adhesion GPCR functions
Graphical Abstract Abstract Unlike conventional G-protein-coupled receptors (GPCRs),
adhesion GPCRs (aGPCRs) have large extracellular regions that are autoproteolytically …
adhesion GPCRs (aGPCRs) have large extracellular regions that are autoproteolytically …
The relevance of genomic signatures at adhesion GPCR loci in humans
P Kovacs, T Schöneberg - … and pharmacological principles in health and …, 2016 - Springer
Graphical Abstract Abstract Adhesion G protein-coupled receptors (aGPCRs) have a long
evolutionary history dating back to very basal unicellular eukaryotes. Almost every …
evolutionary history dating back to very basal unicellular eukaryotes. Almost every …
Control of skeletal muscle cell growth and size through adhesion GPCRs
JP White - Adhesion G Protein-coupled Receptors: Molecular …, 2016 - Springer
Graphical Abstract Abstract Skeletal muscle homeostasis is regulated by a constant influx of
chemicals and exposure to mechanical stimuli. A number of key signaling pathways that …
chemicals and exposure to mechanical stimuli. A number of key signaling pathways that …
Heart development, angiogenesis, and blood-brain barrier function is modulated by adhesion GPCRs
Graphical Abstract Abstract The cardiovascular system in adult organisms forms a network of
interconnected endothelial cells, supported by mural cells and displaying a high degree of …
interconnected endothelial cells, supported by mural cells and displaying a high degree of …