Pathogenesis of alcoholic liver disease
W Dunn, VH Shah - Clinics in liver disease, 2016 - liver.theclinics.com
Alcoholic liver disease (ALD) includes a broad spectrum of disorders, such as simple
steatosis, cirrhosis, acute alcoholic hepatitis (AH) with or without cirrhosis, and …
steatosis, cirrhosis, acute alcoholic hepatitis (AH) with or without cirrhosis, and …
An overview of natural plant products in the treatment of hepatocellular carcinoma
Background: Liver cancer is the fifth most commonly diagnosed cancer and the second
leading cause of cancer-related deaths worldwide. Among the liver cancers, hepatocellular …
leading cause of cancer-related deaths worldwide. Among the liver cancers, hepatocellular …
[HTML][HTML] Simultaneous binding of quercetin and catechin to FOXO3 enhances IKKα transcription inhibition and suppression of oxidative stress-induced acute alcoholic …
H Guan, W Zhang, H Liu, Y Jiang, F Li, D Wang… - Journal of Advanced …, 2025 - Elsevier
Introduction Oxidative stress is one of the major contributors to acute alcoholic liver injury
(AALI), which is a common alcoholic liver disease. Quercetin and catechin are flavonoid …
(AALI), which is a common alcoholic liver disease. Quercetin and catechin are flavonoid …
[HTML][HTML] Role of farnesoid X receptor and bile acids in alcoholic liver disease
S Manley, W Ding - Acta Pharmaceutica Sinica B, 2015 - Elsevier
Alcoholic liver disease (ALD) is one of the major causes of liver morbidity and mortality
worldwide. Chronic alcohol consumption leads to development of liver pathogenesis …
worldwide. Chronic alcohol consumption leads to development of liver pathogenesis …
[HTML][HTML] Protein arginine methylation in viral infection and antiviral immunity
K Zheng, S Chen, Z Ren, Y Wang - International journal of …, 2023 - ncbi.nlm.nih.gov
Protein arginine methyltransferase (PRMT)-mediated arginine methylation is an important
post-transcriptional modification that regulates various cellular processes including …
post-transcriptional modification that regulates various cellular processes including …
[HTML][HTML] New advances in molecular mechanisms and emerging therapeutic targets in alcoholic liver diseases
JA Williams, S Manley, WX Ding - World journal of …, 2014 - ncbi.nlm.nih.gov
Alcoholic liver disease is a major health problem in the United States and worldwide.
Chronic alcohol consumption can cause steatosis, inflammation, fibrosis, cirrhosis and even …
Chronic alcohol consumption can cause steatosis, inflammation, fibrosis, cirrhosis and even …
High-throughput sequencing reveals altered expression of hepatic microRNAs in nonalcoholic fatty liver disease–related fibrosis
F Leti, I Malenica, M Doshi, A Courtright… - Translational …, 2015 - Elsevier
Recent evidence suggests that microRNAs (miRNAs), small, noncoding RNA molecules that
regulate gene expression, may play a role in the regulation of metabolic disorders, including …
regulate gene expression, may play a role in the regulation of metabolic disorders, including …
CYP2E1-dependent upregulation of SIRT7 is response to alcohol mediated metastasis in hepatocellular carcinoma
C Zhang, J Zhao, J Zhao, B Liu, W Tang, Y Liu… - Cancer gene …, 2022 - nature.com
Long-term alcohol use is a confirmed risk factor of liver cancer tumorigenesis and
metastasis. Multiple mechanisms responsible for alcohol related tumorigenesis have been …
metastasis. Multiple mechanisms responsible for alcohol related tumorigenesis have been …
Serine 574 phosphorylation alters transcriptional programming of FOXO3 by selectively enhancing apoptotic gene expression
Z Li, J Zhao, I Tikhanovich, S Kuravi… - Cell Death & …, 2016 - nature.com
Abstract Forkhead box O3 (FOXO3) is a multispecific transcription factor that is responsible
for multiple and conflicting transcriptional programs such as cell survival and apoptosis. The …
for multiple and conflicting transcriptional programs such as cell survival and apoptosis. The …
FOXO3-dependent apoptosis limits alcohol-induced liver inflammation by promoting infiltrating macrophage differentiation
Z Li, J Zhao, S Zhang, SA Weinman - Cell Death Discovery, 2018 - nature.com
Alcohol consumption is generally well tolerated by the liver but in some individuals it results
in persistent inflammation and liver disease. The mechanisms that regulate alcohol-induced …
in persistent inflammation and liver disease. The mechanisms that regulate alcohol-induced …